نتایج جستجو برای: cd40 ligand

تعداد نتایج: 111367  

2015
Hyemin Kim Yejin Kim Seyeon Bae Joo Myoung Kong Jiwon Choi Mirim Jang Jiyea Choi Jun-man Hong Young-il Hwang Jae Seung Kang Wang Jae Lee

It has recently been reported that the CD40-CD40 ligand (CD40L) interaction is important in Th17 development. In addition, transforming growth factor-beta (TGF-β) promotes tumorigenesis as an immunosuppressive cytokine and is crucial in the development of Th17 cells. This study investigated the role of CD40 in breast cancer cells and its role in immunosuppressive function and tumor progression....

Journal: :Transactions of the American Ophthalmological Society 2014
Raymond S Douglas Tünde Mester Anna Ginter Denise S Kim

PURPOSE To better understand the pathogenesis of thyroid-associated orbitopathy (TAO) through elucidating the role of thyrotropin receptor (TSHR) and CD40 in the expression of interleukin-8 (IL-8) in peripheral blood fibrocytes. Fibrocytes infiltrate the orbit of patients with TAO, where they differentiate into fibroblasts. Fibrocyte precursors occur with increased frequency in the peripheral b...

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