Congenital midline cervical cleft is a rare anomaly that typically presents in the neonatal period as a thin suprasternal vertical band of erythematous skin with a nipple-like projection superiorly, which may exude fluid. We present the clinical and pathophysiologic features and the imaging findings of this uncommon, and rarely described entity in a newborn girl.

This study was conducted to develop a detailed, nonlinear three-dimensional geometrically and mechanically accurate finite-element model of the human lower cervical spine using a high-definition digitizer. This direct digitizing process also offers an additional method in the development of the finite-element model for the human cervical spine. The biomechanical response of the finite-element m...

background & objectives: tumor diathesis (td) is defined as granular proteinaceous precipitates on slide surface of cytologic smears. it is found in the background of smears of invasive carcinoma but not in all cases. the aim of present study was to determine the prevalence of td in cervicovaginal smears from patients with uterine cervix carcinoma. methods: cytological smears and histologi...

Ingestion of amniotic fluid or placenta by rats has been shown to enhance several types of opioid-mediated analgesia: that induced by morphine, footshock, vaginal/cervical stimulation, and late pregnancy. This enhancement has also been blocked by administration of opioid antagonists. The present study was designed to examine further the specificity of the enhancement effect for opioid-mediated ...

OBJECT Syringomyelia causes progressive myelopathy. Most patients with syringomyelia have a Chiari I malformation of the cerebellar tonsils. Determination of the pathophysiological mechanisms underlying the progression of syringomyelia associated with the Chiari I malformation should improve strategies to halt progression of myelopathy. METHODS The authors prospectively studied 20 adult patie...

Vaginal colonization and symptomatic vaginitis involving Candida albicans is common during pregnancy (1,2); however, infection of the amniotic fluid in the presence of intact membranes is encountered rarely in obstetrical practice and mostly recognized retrospectively (3). C albicans is able to cross intact fetal membranes (4) and several case reports describe the isolation of the organism from...

RATIONALE Although cervical foreign bodies have been previously reported, the report of a needle in the cervical spinal cord is rare. Herein, we report a rare case of a sewing needle in contact with the cervical dura mater and vertebral artery. PATIENTS CONCERNS A 47-year-old man presented with discomfort in the posterior region of his neck. Approximately 2 years before admission, he suffered...

An 81-year old woman with a history of chronic lymphocytic leukemia (CLL) was admitted with night sweats and abdominal distension. A complete blood count showed hemoglobin 5 g/dL, white blood cell (WBC) count 28.5¥109/L and platelets 38.4¥109/L. Peripheral blood smear examination showed a large number of smudge cells and lymphocytosis composed of mature-looking lymphocytes with clumped nuclear ...

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature. Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The mechanism of CSF entry into the LNs has been unclear. Here we report the surprising finding of a lymphatic vessel network in the dura mater of the mouse brain. We show that dural lymphatic vessels absorb CSF from the ...

Lactoferrin (Lf) is an approximately 80-kDa iron-binding glycoprotein, belonging to the transferrin family, with well-known bacteriostatic and bactericidal properties. It is produced and stored in specific (secondary) neutrophil granules and released during neutrophil activation and degranulation. Nowadays, Lf has a well-known therapeutic indication for combating iron deficiency anemia (IDA) in...