We performed a retrospective analysis of the clinical features and patient outcomes for advanced-stage glassy cell carcinoma of the uterine cervix. The study was restricted to cases in which the glassy cell features constituted at least 95% of the biopsied specimen. During the study period, 675 patients were diagnosed with primary cervical carcinoma. Five (0.7%) of the 675 patients had cervical...

Sex-determining region Y-box 9 protein (SOX9) is a transcription factor that may act as both oncogene and tumor suppressor depending on tumor origin. Here we found that SOX9 expression was progressively decreased in cervical carcinoma in situ and especially in invasive cervical carcinoma, compared with normal cervix tissue. The effects of SOX9 on the proliferation, viability, and tumor formatio...

A 48-year-old man was referred to our unit for assessment of recurring episodes of painful torticollis. Family and past histories were unremarkable. There was no traumatic antecedent. During the previous three years he had experienced several episodes of torticollis and painful cervical movements without radiculopathy. His neurological examination was normal, except for a head tilt, decrease ra...

Samir, R. 2015. Tissue tumor marker expression in normal cervical tissue and in cervical intraepithelial neoplasia, for women who are at high risk of human papilloma virus infection, are smokers, contraceptive users or in fertile age. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1137. 74 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9348-6...

gammagraphy may be normal or show multiple small, peripheral repletion defects. The diagnosis of pulmonary tumor embolism requires finding tumor cells in the lung vasculature. Cervical cancer is the second most frequent cause of morbidity and mortality related with cancer among women in developing countries: 371,200 new cases each year, with a 50% mortality rate. The incidence of invasive cervi...

Introducción: El espacio parafaríngeo es un anatómico complejo. Los tumores que surgen en esta región son raros y la cirugía constituye primera opción de tratamiento mayoría los casos(1). Aunque tradicionalmente las masas gran tamaño este se abordan forma transcervical, transoral robótica (TORS) aporta grandes ventajas, siendo más segura, menos mórbida potencialmente efectiva, mejorando clarame...

PURPOSE Cervical cancer cells are addicted to the expression of the human papillomavirus (HPV) oncoproteins E6 and E7. The oncogencity of E6 is mediated in part by targeting p53 and PDZ-family tumor suppressor proteins for rapid proteasomal degradation, whereas the E7 oncoprotein acts in part by coopting histone deacetylases (HDAC)1/2. Here, we examine the hypothesis that inhibition of proteaso...