Low density lipoprotein receptor (LDLR) was shown to mediate clearance of blood coagulation factor VIII (FVIII) from the circulation. To elucidate the mechanism of interaction of LDLR and FVIII, our objective was to identify the region of the receptor necessary for binding FVIII. Using surface plasmon resonance, we found that LDLR exodomain and its cluster of complement-type repeats (CRs) bind ...

Wireless sensor networks have recently emerged as an important computing platform. Energy conservation and maximization of network lifetime are commonly recognized as a key challenge in the design and implementation of wireless sensor networks. Clustering provides an effective method for prolonging the lifetime of a wireless sensor network. In this paper, we propose an Energy Efficient Cluster-...

Melting of crystalline solids ~superlattices! of octadecanethiol and octanethiol protected silver clusters has been studied with x-ray powder diffraction ~XRD!, differential scanning calorimetry ~DSC!, and infrared ~IR! spectroscopy. These solids have been compared with the silver thiolate layered compounds in view of their similarity in alkyl chain packing and x-ray diffraction patterns. Super...

Wireless sensor networks are composed of a large number of sensors densely deployed in inhospitable physical environments. How to disseminate information energy efficiently throughout such a network is still a challenge. Although energy efficiency is a key concern in wireless sensor networks, it often introduces additional delay. In this work, we first propose an Energy*Delay efficient routing ...

With the increase in the number of studies on supply chain management practices and their application, many studies have proposed methodologies that can be used by manufacturers to evaluate vendors. These methodologies allow a buyer to choose several specific indicators or multiple criteria to evaluate vendors and distinguish them from one another based on their performance. Manufacturers can t...

Recently the bkd gene cluster from Enterococcus faecalis was sequenced, and it was shown that the gene products constitute a pathway for the catabolism of branched-chain alpha-keto acids. We have now investigated the regulation and physiological role of this pathway. Primer extension analysis identified the presence of a single promoter upstream of the bkd gene cluster. Furthermore, a putative ...

Iron-sulfur (Fe-S) clusters are ubiquitous cofactors composed of iron and inorganic sulfur. They are required for the function of proteins involved in a wide range of activities, including electron transport in respiratory chain complexes, regulatory sensing, photosynthesis and DNA repair. The proteins involved in the biogenesis of Fe-S clusters are evolutionarily conserved from bacteria to hum...

background: the tan spot disease of wheat caused by pyrenophera tritici-repentis has become a major disease in most wheat growing areas worldwide. objectives: here we used issr and rapd markers to study the genetic diversity of 34 p. tritici-repentis isolates collected from north of iran.materials and methods: the leaves having the typical symptoms of tan spot disease were collected and after f...

In this paper we propose a traffic model for delivering scalable video encoded with multiple layers on heterogeneous networks. The model is based on Markovian arrival process with marked transitions. The state of the underlying Markov chain of the video arrival process is derived from the correlation feature found in the video data. The base layer and enhancement layer video frame size pairs ar...

Wireless Sensor Networks consist of small nodes with sensing, computation and wireless communication capabilities. In general, sensor nodes have some limitations such as limited battery power, storage capability and restricted computing ability. So it is essential to design effective and energy aware protocols in order to prolong the network lifetime. PEGASIS is one of the well-known chain-base...