G protein-coupled receptor (GPCR) signaling is affected by formation of GPCR homo- or heterodimers, but GPCR regulation by other cell surface proteins is not well understood. We reported that the kinin B1 receptor (B1R) heterodimerizes with membrane carboxypeptidase M (CPM), facilitating receptor signaling via CPM-mediated conversion of bradykinin or kallidin to des-Arg kinin B1R agonists. Here...

Abstract—A broadband dual-feed dual-polarized microstrip antenna with low cross polarization and high isolation is presented. The dualorthogonal linearly polarized mode is excited by two different feed mechanisms from a single circular radiating patch. One of the two modes is excited by a pair of L-shaped probes with a 180◦ phase differences, and the other is excited by an H-shaped aperture. Th...

Managing corporate performance is an important yet challenging process. Recently, many enterprises have adopted business intelligence (BI) tools to facilitate more effective corporate performance management. Based on a survey with 290 organizations across North America and East Asia, this paper presents empirical evidence on the key benefits of and barriers to BI-based corporate performance man...

The support of PLM throughout the product life, from the product’s conceptualization to its disposal, requires reliable, complete and efficient data models. The Core Product Model (CPM), initially developed at NIST for a number of in-house research projects, has been extended so as to support the full range of PLM information. CPM gives equal status to three aspects of a product or artifact: it...

Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a...

Central pontine myelinolysis (CPM), a potentially fatal and debilitating neurological condition, was first described in 1959 in a study on alcoholic and malnourished patients. It is a condition most frequently related to rapid correction of hyponatremia. Chronic alcoholism associated CPM tends to be benign with a favorable prognosis compared to CPM secondary to rapid correction of hyponatremia....

Continuous phase modulation (CPM) is a widely used modulation scheme in communication systems. However, difficulties arise with the design of CPM receivers, due to the nonlinear nature of CPM. One popular solution is to linearize CPM with pulse amplitude modulation (PAM) representation. In this paper, a reduced-complexity non-dataaided (NDA) timing recovery method for PAM-based M-ary CPM receiv...

The paper presents a conceptual model for assessing the maturity of a Corporate Performance Management (CPM) in an organization. The CPM maturity development process was studied in five case companies where the author participated into CPM development projects in various consultation roles. Constructive and action-oriented research approaches were used with different methods for data collection...

A novel time domain multiplexed (TDM) spatial division multiplexing (SDM) receiver which allows for the reception of >1 dual polarization mode with a single coherent receiver, and corresponding 4-port oscilloscope, is experimentally demonstrated. Received by two coherent receivers and respective 4-port oscilloscopes, a 3 mode transmission of 28GBaud QPSK, 8, 16, and 32QAM over 41.7km of few-mod...

Why has the Critical Path Method (CPM) been used so widely for so long given its inability to produce predictable outcomes? For shedding light on this paradox, the formative period of the CPM is analysed from two main angles. First, how was the CPM embedded into the construction management practice? Second, what was the methodological underpinning of the development of the CPM? These questions ...