Abstract We propose an efficient high-throughput scheme for the discovery of stable crystalline phases. Our approach is based on transmutation known compounds, through substitution atoms in crystal structure with chemically similar ones. The concept similarity defined quantitatively using a measure chemical replaceability, extracted by data-mining experimental databases. In this way we build 18...

A group of experiments is presented in which inhibition of chemical carcinogenesis in experimental animals has been achieved by administration of 1 of a variety of chemical com pounds. The inhibitory compounds can be divided into 4 groups. The 1st group is composed of compounds which induce an in creased activity of carcinogen-detoxifying systems; the 2nd, compounds with similar structures to c...