OBJECTIVES In order to elucidate the influence of sympathetic nerves on lumbar radiculopathy, we investigated whether sympathectomy attenuated pain behaviour and altered the electrical properties of the dorsal root ganglion (DRG) neurons in a rat model of lumbar root constriction. METHODS Sprague-Dawley rats were divided into three experimental groups. In the root constriction group, the left...

AIM To study the influence of sympathectomy on nerve regeneration in human extremities. MATERIAL AND METHODS Autoneuroplasty was performed in 86 patients with posttraumatic defects of median and ulnar nerves: in 42 cases in combination with sympathectomy (thoracoscopic clipping of Th3-4 sympathetic ganglions) and in 44 cases without sympathectomy. Computer thermography, laser Doppler flowmetr...

The past few years have seen a steady progress in the determination of element abundances at high redshifts, with new and more accurate measures of metallicities in star-forming galaxies, in QSO absorbers, and in the intergalactic medium. We have also become more aware of the limitations of the tools at our disposal in such endeavours. I summarise these recent developments and—in tune with the ...

The chemical industry poses a potential security risk to factory personnel and neighboring residents. In order to mitigate prospective damage, a synthetic method must be developed for an emergency response. With the development of environmental numeric simulation models, model integration methods, and modern information technology, many Decision Support Systems (DSSs) have been established. How...

Guanethidine, a chemical that selectively blocks sympathetic noradrenergic neurons, was used to investigate the role of sympathetic innervation in the fertility of rat epididymal sperm, using both natural mating and in utero insemination protocols. This animal model correlates, at least in part, with spinal cord injury (SCI) in men. Adult male rats were treated daily by i.p. injections, for 21 ...

In this work, we examine whether tenth-grade high school students (N = 197, age 1516) as well as first-year university chemistry students (N = 77, age 18-19) can make the connection between chemical reactions and chemical phenomena. We used nineteen physical and chemical phenomena, and asked the students at one stage to distinguish physical from chemical phenomena, and at another stage to state...

Rates of protein synthesis were investigated in skeletal muscles from rats submitted to chemical and surgical sympathectomy. Three models of sympathetic denervation were used: 1) treatment with guanethidine (100 mg.kg(-1).day(-1) sc); 2) lumbar sympathetic denervation (surgical excision of the second and third lumbar ganglia of the sympathetic chain, from which arises the postganglionic fibers ...

OBJECTIVE Leptin reverses hyperglycemia in rodent models of type 1 diabetes (T1D). Direct application of leptin to the brain can lower blood glucose in diabetic rodents, and can activate autonomic efferents and non-shivering thermogenesis in brown adipose tissue (BAT). We investigated whether leptin reverses hyperglycemia through a mechanism that requires autonomic innervation, or uncoupling pr...