INTRODUCTION Of the approximately 12,000 children and adolescents that will be diagnosed with cancer in 2013, it is expected that over 80% of them will become long-term adult survivors of childhood cancer. Although it has been well established that cancer treatment often has profound negative impact on sexual functioning, sexual functioning in adult survivors of childhood cancer is not well und...

Past research has not adequately addressed the quality of life (QOL) of survivors of childhood cancer. The purpose of this study was to understand how QOL is experienced for individuals who have survived childhood cancer. Specific research questions included: (a) How do childhood cancer survivors define the concept of QOL and (b) What processes do childhood cancer survivors go through regarding...

Objective To assess risk of cancer in patients with childhood onset inflammatory bowel disease in childhood and adulthood.Design Cohort study with matched general population reference individuals using multivariable Cox regression to estimate hazard ratios.Setting Swedish national patient register (both inpatient and non-primary outpatient care) 1964-2014.Participants Incident cases of childhoo...

Advancements in cancer treatments have increased the number of survivors of childhood cancers. Endocrinopathies are common complications following cancer therapy and may occur decades later. The objective of the current review is to address the main endocrine abnormalities detected in childhood cancer survivors including disorders of the hypothalamic-pituitary axis, thyroid, puberty, gonads, bo...

Improved treatment strategies and better supportive care have resulted in increased survival rates for childhood cancers. However, most of the survivors may have complex, long-term health issues. In 2004, Childhood Cancer Survivorship Study of the United States confirmed that both survivors and the medical community need to be educated about the late effects of childhood cancer treatment. Korea...

background: environment of basrah is seriously contaminated with chemical leukomogens as a result of recent military conflicts. many studies in the past few years have reported an increase in the incidence of leukemia in basrah. this study was designed to study the risk and pattern of childhood leukemia in basrah, iraq, from 2003 to 2007.materials and methods: this hospital-based cancer registr...

Background: Environment of Basrah is seriously contaminated with chemical leukomogens as a result of recent military conflicts. Many studies in the past few years have reported an increase in the incidence of leukemia in Basrah. This study was designed to study the risk and pattern of childhood leukemia in Basrah, Iraq, from 2003 to 2007.Materials and Methods: This hospital-based cancer registr...

Progress in the study and treatment of childhood cancer is arguably the most remarkable and rewarding story of cancer therapy in the past five decades. During this time, five-year survival rates have steadily increased and now exceed 80% in developed countries for all pediatric cancer sites (Fig 1). With the expectation of extended survival into adulthood for most childhood patients with cancer...

Cardiovascular complications are a leading cause of therapy-related morbidity and mortality in long-term survivors of childhood malignancy. In fact, childhood cancer survivors are at a 15-fold risk of developing CHF compared to age-matched controls. There is a strong dose-dependent association between anthracycline exposure and risk of CHF, and the incidence increases with longer followup. Outc...

OBJECTIVE To investigate whether adolescent siblings of childhood cancer survivors experience posttraumatic stress (PTS). METHODS Participants included 78 adolescent siblings of adolescent cancer survivors who completed self-report measures of anxiety, PTS, and perceptions of the cancer experience. RESULTS Nearly half (49%) of our sample reported mild PTS and 32% indicated moderate to sever...