New anticancer drugs are developed separately in children because of potential differences in drug disposition, tissue/organ sensitivity to the drug’s toxic effects and pathogenesis and tissue of origin of childhood cancers compared with cancers in adults. The focus of new drug development for childhood cancers has shifted to molecularly targeted drugs that selectively inhibit cell-signaling pa...

BACKGROUND Studies have shown that higher solar UV radiation exposure (UVR) may be related to lower risk of some cancers in adults. Recently, an ecologic study reported lower risks of some cancers among children living in higher UVR cities and countries. In a large population-based case-control study in California, we tested the hypothesis that childhood cancers may be influenced by UVR. METH...

INTRODUCTION To present the work previously and presently being carried out based on the nationwide Childcare Database. RESEARCH TOPICS The Childcare Database comprises individually linked Danish register-based data on childcare attendance, childcare facility characteristics, child and family characteristics, and infectious disease hospitalisations. The database includes about 1 million child...

conclusions carcinomas were the most common malignant tumors of head and neck observed in this age group. also, oral cancers in children and adolescents constitute a small percentage of the lesions that were studied objectives we aimed to determine the frequency of head and neck cancers in a population of iranian children and adolescents. patients and methods the records of patients ≤ 19 years ...