Osteosarcoma, the most common bone cancer, leads to a poor survival rate of patients. Drug targeting employing hydroxyapatite (HAp)-based nanocarriers represents fascinating choice for non-invasive treatment osteosarcoma.

Osteosarcoma (osteogenic sarcoma: OS) is the most common primary malignant bone tumor of long bones, whereas primary osteosarcoma of chest wall, especially in sternum, is extremely rare. We report a 57-year-old man with an immobile slow growing mass located in the middle of the sternum. The patient had no significant pain or tenderness and the past medical history was not remarkable. CT-scan sh...

epitheloid osteosarcoma (carcinosarcoma) of the bone is a rare malignant tumor and only a few cases have been reported in the literature. in this study, we report two cases of osseous carcinosarcoma (epitheloid osteosarcoma) with immunohistochemical studies.  the morphological and immunohistochemical data in these two cases support the theory of divergent differentiation of primitive, uncommitt...

Giant cell-rich osteosarcoma of the jaw (JGCRO) is very rare but it diagnostically important because its poor prognosis compared to other variants osteosarcoma. We report a case recurrent JGCRO initially diagnosed as an ossifying fibroma. The clinical presentation, radiologic and histologic features intermediate outcome treatment are highlighted.

osteosarcoma (os) is a malignant mesenchymal tumor, which rarely occurs in the maxilla. although variable histologic and radiographic features of os have been reported previously, in the majority of the cases painful swelling of the jaw is mentioned as the first clinical presentation. furthermore, early diagnosis and wide surgical resection of the tumor are the most important determinant factor...

1. Abstract 2. Introduction 3. PET/CT in the diagnosis of osteosarcoma 3.1. PET/CT in the diagnosis of pediatric osteosarcoma 3.2. PET/CT in the differential diagnosis between osteosarcoma and mimic diseases 3.3. PET/CT in the diagnosis of rare cases 4. PET/CT in the relapse of osteosarcoma 5. PET/CT in the metastases of osteosarcoma 6. PET/CT in the histological response to neoadjuvant chemoth...

Background & Aims: Osteosarcoma is one of the most prevalent malignant bone tumors . This study is designed to assess the prognostic effect of pathologic fracture and treatment options on survival of patients with osteosarcoma. Materials & Methods: In this study, prognosis of 106 patients with limb osteosarcoma, which were treated at three  hospitals in Tehran from April to August 2012 ...

osteosarcoma is a relatively uncommon malignancy however, it is the most common form of primary malignant bone tumors in human. diagnosis and prognosis of patients with osteosarcoma is limited to clinico-radiopathological parameters, whereas molecular markers of tumor aggression have been poorly identified. survivin, an inhibitor of apoptosis (iap), is unique for its expression in human tumors ...

hereby we report a case of well-differentiated intraosseous osteosarcoma in the sacrum. a 32-year-old woman was admitted to our hospital with a low echo-level mass in the pelvis searched by ultrasound in a routine physical examination. radiographically, the mass was misdiagnosed as a benign bony tumor originating from the sacrum. the tumor was completely resected and pathological diagnosis was ...

it is sometimes difficult to recognize a jaw lesion as osteosarcoma, ossifying fibroma or ‎fibrous dysplasia in routine hematoxylin and ‎eosin staining and a more accurate technique is needed to differentiate these ‎lesions. ‎many studies have shown the potential usefulness of silver-stained nucleolar organizer region (agnor) parameters for the diagnosis of various neoplasms. this study was car...