Chronic or persistent viral infections, like HBV, HCV and HIV, are still a challenge for human health. More importantly, most human chronic viral infection will result in cancer, the top leading cause of death. So far antiviral drugs and immunotherapy have limited therapeutic effects on patients. New potential mechanisms of chronic viral infections are needed to explore before new effective the...

during a 30-month period. 2s patients with deep infected median sternotomy wounds were managed surgically. fifteen patients had chronic sternal osteomyelitis with associated costochondruis, 7 patients had only costochondritis, and 3 patients had dehiscence and/or mediastinitis. twenty were male and 5 were female their ages rangedfrom 11 to 71 years. nine patients had 11 failed previous attempts...