introduction: it has been shown that the extract of elaeagnus angustifolia can inhibit inflammation and pain induced by formalin in mice and rats. the aim of the present study is to reach evaluations of possible cellular and molecular mechanisms of elaeagnus angustifolia extract in reducing pain and inflammation through examining the extract ability for inhibition of cyclooxygenase (cox) type 1...

Obesity can be considered as a chronic, systemic low-grade inflammation state induced by different inflammatory cytokines. The chronic inflammation in obesity may be a result of hypoxia in adipose tissue, macrophage infiltration to vascular wall and endocytoplasmic reticulum stress. Studies have shown that long-time regular exercise training can lower the levels of inflammatory markers and redu...

The review presents modern aspects of the epidemiology, pathogenesis, diagnosis, drug treatment chronic prostatitis. We performed a comprehensive search using multiple databases. There is still no single pharmacological approach in management patients with prostate. Future clinical trials should include full report their methods including adequate masking, consistent assessment all patient-impo...

Gastric cardia cancer (GCC) is a highly aggressive disease associated with chronic inflammation. To investigate the relationship between DNA damage response (DDR) and chronic inflammation, we collected 100 non-tumor gastric cardia specimens of Chaoshan littoral, a high-risk region for esophageal and gastric cardia cancer. A significantly higher proportion of severe chronic inflammation was foun...