Background: Multiple sclerosis (MS) is one of the most common chronic diseases of the central nervous system. The aim of this study was to determine the effectiveness of psychological training combined‎ with gradual muscular stress relaxation technique on QOL of patients with MS. Materials and Methods: This triple-blind, controlled, clinical trial was conducted on 60 patients with MS who...

background: parents of children with developmental problems are always bearing a load of stress. the aim of this study is to compare the stress in mothers of children with different disabilities to each other, considering their demographic background. materials and methods: this was a cross-sectional study conducted in isfahan, iran during 2012 on 285 mothers of 6-12 years old children with chr...

Stress has a strong impact in the brain, impairing decision-making processes as a result of changes in circuits involving the prefrontal and orbitofrontal cortices and the striatum. Given that these same circuits are key for action control and outcome encoding, we hypothesized that adaptive responses to which these are essential functions, could also be targeted by stress. To test this hypothes...

The population of persons living with HIV (PLWH) is growing older and more prone to developing other chronic health conditions. Disease progression has been shown to be related to quality of life (QoL). However, descriptions of chronic comorbid illnesses and the unique QoL challenges of older adults living with HIV are not well understood and have not been examined in multiple geographic locati...

This work deals with a general problem of testing multiple hypotheses about the distribution of a discrete-time stochastic process. Both the Bayesian and the conditional settings are considered. The structure of optimal sequential tests is characterized.

MOTIVATION In molecular biology, as in many other scientific fields, the scale of analyses is ever increasing. Often, complex Monte Carlo simulation is required, sometimes within a large-scale multiple testing setting. The resulting computational costs may be prohibitively high. RESULTS We here present MCFDR, a simple, novel algorithm for false discovery rate (FDR) modulated sequential Monte ...

based on the evidence regarding the relationship between inflammatory processes and stress responses, the present study investigated the association between psychological stress and elevation of inflammatory mediators related to periodontal disease in adult patients.the study consisted of 50 patients including 25 patients with chronic periodontitis and 25 cases with aggressive periodontitis. tw...

This paper considers dynamic games in which multiple principals contract sequentially and noncooperatively with the same agent. We first show that when contracting is private, i.e. when downstream principals do not observe the mechanisms offered upstream and the decisions taken in these mechanisms, all PBE outcomes can be characterized through pure-strategy profiles in which the principals offe...

Several lines of research on human and rodent subjects have demonstrated that early-life stress results in multiple negative outcomes, including increased incidence of psychopathologies. The current study sought to further the research on adolescent versus adult rats on anxiety-like reactions to chronic stress. The purpose of the current study was to assess whether 7 days of chronic restraint s...