Haemophilus parainfluenzae is often isolated from the sputa of patients with chronic obstructive lung disease. We have investigated the immune response to this organism in patients with chronic bronchitis (n = 3) and bronchiectasis (n = 10) and in healthy controls (n = 9). Outer membrane proteins (OMPs) of H. parainfluenzae were purified for use in enzyme-linked immunosorbent and immunoblot ass...

Background: Breathlessness is a multifactorial problem caused by multiple pathways and thus lends itself to a range of interventions, each targeting a specific mechanism. For a start, the aging process affects respiratory function and decreases lung elasticity and respiratory muscle strength, which results in forced vital capacity reduction. Moreover, many conditions, such as chronic obstructiv...

Gimeno, F., Berg, W. Chr., Steenhuis, E. J., de Vries, K., Peset, R., and Sluiter, H. J. (1974). Thorax, 29, 16-20. Exercise-induced airway obstruction in relation to chronic obstructive lung disease. Forty-two patients with chronic obstructive lung disease and clinically suspected exercise-induced airway obstruction were studied to ascertain whether those with proven exercise-induced airway ob...

Introduction: Forced expiratory value in one score  (FEV1)/ Forced vital capacity (FVC) was used in classical literature for primary classifications of pulmonary disorders. American Thoracic Society/ European Respiratory Society guidelines recommended using FEV1/VC instead of FEV1/FVC.The aim of study was determination of the extent of superiority of FEV1/VC over the FEV1/FVC. Materials and Met...

Changes in renal function have been reported in chronic obstructive lung disease' but not proteinuria. We describe a heterogeneous group of patients with chronic obstructive lung disease who were found to have microalbuminuria. Patients, methods, and results Twenty two inpatients with chronic obstructive lung disease provided a clean catch midstream specimen of urine. Twenty normal healthy volu...

The present study aimed to measure physical activity in patients with chronic obstructive pulmonary disease (COPD) to: 1) identify the disease stage at which physical activity becomes limited; 2) investigate the relationship of clinical characteristics with physical activity; 3) evaluate the predictive power of clinical characteristics identifying very inactive patients; and 4) analyse the reli...

BACKGROUND An important prerequisite for the Chronic Care Model is to be able to identify, in a valid, simple and inexpensive way, the population with a chronic condition that needs proactive and planned care. We investigated if a set of administrative data could be used to identify patients with Chronic Obstructive Pulmonary Disease in a Danish population. METHODS Seven general practices wer...

introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...

BACKGROUND A substantial proportion of the general population has low lung function, and lung function is known to decrease as we age. Low lung function is a feature of several pulmonary disorders, such as uncontrolled asthma and chronic obstructive pulmonary disease. The objective of this study is to investigate the association of polymorphisms in asthma and chronic obstructive pulmonary disea...