objective(s):micrornas (mirnas) are small non-coding rna molecules that regulate gene expression. they have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (ckd). in the present study, we elucidated the role of micror...

nonencapsulated, nontypeable hemophilus influenzae (nthi) remains an important cause of acute otitis and respiratory diseases in children and adults. nthi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. the bacteria can also cause chronic dise...

conclusions the fev1/fev6 ratio can be used as a valid surrogate for fev1/fvc in the diagnosis of airway obstruction, especially for screening purposes in high-risk populations for copd. moreover, fev6 is an acceptable alternative for fvc in detection of restrictive pattern. results this study shows that the current cut-off points used to detect obstruction and restriction can be replaced by fe...

background: the objective of this study is to assess the safety and preventative effects of aminophylline on the incidence of chronic lung disease (cld) in very premature infants. methods: this was a long follow‑up randomized clinical trial. the prophylactic effect of aminophylline on the incidence of cld was investigated in very premature infants. the study group received aminophylline for the...

results the results showed that the means of patients' expectations were more than their perceptions of the quality of provided services in all dimensions, which indicated that there were gaps in all dimensions. the highest and lowest means of negative gaps were related to empathy (-0.52 ± 0.48) and tangibility (-0.29 ± 0.51). in addition, among the studied patients' demographic characteristics...

occupational exposure to heavy metals, organic solvents and silica is associated with a variety of renal manifestations. improved understanding of occupational renal disease provides insight into environmental renal disease, improving knowledge of disease pathogenesis. silica (sio 2 ) is an abundant mineral found in sand, rock, and soil. workers exposed to silica include sandblasters, miners, q...

background: chronic kidney disease is asymptomatic until its last stages and though it is increasing globally, we are faced with paucity of a population-based model to assess this disease, particularly in developing countries. therefore, the aim of this study was to estimate the prevalence and trends of ckd according to a new estimation method.   methods: using multiplier method, we estimated t...

background: chronic kidney disease is asymptomatic until its last stages and though it is increasing globally, we are faced with paucity of a population-based model to assess this disease, particularly in developing countries. therefore, the aim of this study was to estimate the prevalence and trends of ckd according to a new estimation method.   methods: using multiplier method, we estimated t...