The lizard Iguana iguana when kept in constant ambient temperature displays endogenously generated circadian rhythms of body temperature and locomotor activity. Although surgical removal of the parietal eye has only slight effects on overt circadian rhythmicity, subsequent pinealectomy completely abolishes the rhythm of body temperature. However, the rhythm of locomotor activity is only slightl...

Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be disrupted. Patients infected with HIV or addicted to drugs of abuse often suffer from sleep disorders and altered circadian rhythms. Early studies in Drosophila suggested that drug seeking behavior might be related to the expression of ...

Multiple studies question the necessity of transcription/translation feedback loops for the generation of circadian rhythms. New data emphasize the necessity of proteasomal degradation for circadian rhythmicity in transcriptionally competent cells.

The effects of light:darkness (LD) cycles and social interaction on the response to long-term confinement (105 days) were investigated experimentally in three groups of three male subjects aged 20-24 years. Data from measurements of physiological parameters indicating changes in circadian rhythms are presented in graphs and analyzed; it is found that the LD-induced rhythm changes observed in pr...

Recent studies suggest that a class of proteins known as cryptochromes have an evolutionarily conserved role in the entrainment of circadian rhythms to the night-day cycle. While the evidence reported is intriguing, the notion that cryptochromes have the same role in all species requires further investigation.

Within the scope of working areas in residential spaces, home-office method, which is becoming more common as a flexible style, has been examined The relationship between circadian lighting reinforcement system and human biology places from home investigated. In terms interior design setup offices, approaches are taken into consideration, their spatial solutions evaluated point efficiency, conc...

In this Preface to the Journal of Neurochemistry special issue “Circadian Rhythms in Brain”, we summarize recent insights into connections between circadian rhythms and societal concerns related aging food intake, with consequences for healthy or aberrant metabolic homeostasis. The articles were written by leading authors who presented their research at 2019 Congress European Biological Rhythm ...

BACKGROUND Cortisol concentrations in plasma display a circadian rhythm in adults and children older than one year. Earlier studies report divergent results regarding when cortisol circadian rhythm is established. The present study aims to investigate at what age infants develop a circadian rhythm, as well as the possible influences of behavioral regularity and daily life trauma on when the rhy...

A mathematical model for the intracellular circadian rhythm generator has been studied, based on a negative feedback of protein products on the transcription rate of their genes. The study is an attempt at examining minimal but biologically realistic requirements for a negative molecular feedback loop involving considerably faster reactions, to produce (slow) circadian oscillations. The model i...