Since the first isolation in 2002, the metallo-β-lactamase GIM-1 has not been detected outside Germany. The data presented here, for 50 clinical blaGIM-1-positive isolates, including Pseudomonas spp. and Enterobacteriaceae (Enterobacter cloacae, Klebsiella oxytoca, Serratia marcescens, Escherichia coli, and Citrobacter freundii), collected between 2007 and 2012 at the original site in an ongoin...

Limited information is available regarding AmpC β-lactamase (ABL)-producing Enterobacteriaceae compared to extended-spectrum β-lactamase-producing enterobacteria. Since ABL-producing organisms are often resistant to multiple antimicrobial agents, therapeutic options against these pathogens are limited. Among 230 clinical Enterobacteriaceae isolates, 64 (27.8%) were found to produce ABL in our s...

* Universita degli Studi dell'Aquila Dipartimento di Scienze e Tecnologie Biomediche e di Biometria, Cattedre di Chimica Biologica e Biologia Molecolare, Localita Collemaggio, 1-67 100 L'Aquila, Italy, t Laboratoire d'Enzymologie et Service de Microbiologie, Universite de Liege Institut de Chimie, B6, B-4000 Sart Tilman (Liege), Belgium, and I Rijksuniversiiteit-Gent Laboratorium voor Microbiol...

The nucleotide sequence of a 3.1-kb region from the chromosome of the Yersinia enterocolitica O:5b strain IP97 containing the gene for an inducible chromosomal cephalosporinase has been determined. The cephalosporinase gene was homologous to other enterobacterial chromosomal cephalosporinase genes, and it was accompanied by a gene homologous to the regulatory ampR gene. The arrangement of genes...

An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-beta-lactamase VIM-1. bla(VIM-1), along with aacA7, dhfrI, and aadA, was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC-derived gene, not associated with the integ...

Purple urine bag syndrome is an uncommon but particularly striking phenomenon observed in people with urinary catheters and co-existent urinary tract infections. A chemical reaction between plastic and certain bacterial enzymes results in an intense purple urine color. We report a 72 year-old male with a cystostomy. A purple coloration of his urinary drainage bag and tubing was noted in the con...

A new proline based ligand was syn thesized by a convenient procedure. The characterized 1 H NMR, 13 C NMR and IR spectroscopies. Copper (II) Schiff base complexes of 4 --{[2 --(methoxycarbonyl) pyrrolidin yl] methyl} benzoic acid this were synthesized the aforementioned spectroscopy techniques, i.e. IR. Moreover, its bactericidal activity assessed through determination minimum inhibitory conce...