BACKGROUND Empiric treatment for Helicobacter pylori is influenced by antibiotic susceptibility of infecting strains. A rise in the resistance rate to clarithromycin and metronidazole has been reported in pediatric populations. OBJECTIVES To assess the primary and secondary antibiotic resistance of H. pylori isolates in Israeli children and adolescents. METHODS A retrospective review of H. ...

BACKGROUND Helicobacter pylori plays a significant role in gastritis and ulcers. It is a carcinogen as defined by the WHO, and infection can result in adenocarcinomas and mucosa-associated lymphoid tissue lymphomas. In Canada, rates of antimicrobial resistance are relatively unknown, with very few studies conducted in the past 15 years. OBJECTIVE To examine rates of resistance in Sudbury, Ont...

Helicobacter pylori remains one of the most common bacterial infections worldwide. Clarithromycin resistance is the most important cause of H. pylori eradication failures. Effective antibiotic therapies in H. pylori infection must be rapidly adapted to local resistance patterns. We investigated the prevalence of clarithromycin resistance due to mutations in positions 2142 and 2143 of 23SrRNA ge...

Clarithromycin is one of the antibiotics used for the treatment of Helicobacter pylori infections, and clarithromycin resistance is the most important factor when it comes to predicting eradication failure. The present study analyzed H. pylori isolates for the presence of 23S rRNA gene mutations and determined the risk factors associated with resistance among H. pylori isolates collected in Mad...

Background: The ideal combination regimen for Helicobacter pylori (HP) eradication has not yet been determined and the success rate of HP extensively reduced worldwide due to increasing antibiotic resistance. So this multinational multi-center randomized controlled trial was designed evaluate efficacy tetracycline +levofloxacin eradication. Methods: During a 6-month period, all cases with infec...

background antibiotic resistance is a major therapeutic problem in patients infected with helicobacter pylori. h. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rrna point mutations. objectives in the present study, we investigated anti-mutational features of four traditionally iranian medicinal plants on three local isolated h. py...

Background: Helicobacter pylori infection infects approximately 50% of the world’s population, and is associated with significant morbidity and mortality. H. pylori infection is associated with large expenditures for diagnostic testing and prescription medication. Summary: The C13-urea breath test remains the non-invasive test with the highest sensitivity and specificity, and is the test-of-cho...

Sir, Colonization/infection with Helicobacter pylori is contracted during childhood, persists lifelong and causes chronic gastritis, which may be complicated by peptic ulcer disease, gastric cancer or mucosa-associated lymphoid tissue (‘MALT’) lymphoma. Failed H. pylori eradication therapy or antimicrobial therapy due to unrelated infections are the main risk factors for the development of resi...

INTRODUCTION In recent years the failure of standard therapy for Helicobacter pylori infections has been observed, which results primarily from the increasing resistance of H. pylori strains to antibiotics. The aim of the study was to estimate the prevalence of antimicrobial resistance of H. pylori strains isolated from adult symptomatic patients with primary infection in the Lower Silesia Regi...

OBJECTIVE To evaluate Helicobacter pylori resistance to amoxicillin, clarithromycin, metronidazole and tetracycline in Mashhad, Iran. METHODS The cross-sectional study was done from January to May 2008 in Mashhad, involving 185 patients who had been indicated for endoscopy and lesions had been found. Biopsy samples were assessed with histological evaluation, rapid urease test, and culture. An...