نتایج جستجو برای: clfa

تعداد نتایج: 148  

2012
Hua Xiang Yue Feng Jiawei Wang Bao Liu Yeguang Chen Lei Liu Xuming Deng Maojun Yang

Staphylococcus aureus (S. aureus) pathogenesis is a complex process involving a diverse array of extracellular and cell wall components. ClfB, an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules) family surface protein, described as a fibrinogen-binding clumping factor, is a key determinant of S. aureus nasal colonization, but the molecular basis for ClfB-ligand recog...

Journal: :The Journal of infectious diseases 2009
Nelianne J Verkaik Corné P de Vogel Hélène A Boelens Dorothee Grumann Theo Hoogenboezem Cornelis Vink Herbert Hooijkaas Timothy J Foster Henri A Verbrugh Alex van Belkum Willem J B van Wamel

BACKGROUND Persistent carriers have a higher risk of Staphylococcus aureus infections than noncarriers but a lower risk of bacteremia-related death. Here, the role played by anti-staphylococcal antibodies was studied. METHODS Serum samples from 15 persistent carriers and 19 noncarriers were analyzed for immunoglobulin (Ig) G, IgA, and IgM binding to 19 S. aureus antigens, by means of Luminex ...

2013
Wouter L. W. Hazenbos Kimberly K. Kajihara Richard Vandlen J. Hiroshi Morisaki Sophie M. Lehar Mark J. Kwakkenbos Tim Beaumont Arjen Q. Bakker Qui Phung Lee R. Swem Satish Ramakrishnan Janice Kim Min Xu Ishita M. Shah Binh An Diep Tao Sai Andrew Sebrell Yana Khalfin Angela Oh Chris Koth S. Jack Lin Byoung-Chul Lee Magnus Strandh Klaus Koefoed Peter S. Andersen Hergen Spits Eric J. Brown Man-Wah Tan Sanjeev Mariathasan

Infection of host tissues by Staphylococcus aureus and S. epidermidis requires an unusual family of staphylococcal adhesive proteins that contain long stretches of serine-aspartate dipeptide-repeats (SDR). The prototype member of this family is clumping factor A (ClfA), a key virulence factor that mediates adhesion to host tissues by binding to extracellular matrix proteins such as fibrinogen. ...

2011
Christiane Cuny Franziska Layer Birgit Strommenger Wolfgang Witte

MRSA CC130 containing the mecA homologue mecA(LGA251) were reported from the UK and from Denmark so far from cattle and humans. Here we report on 11 MRSA CC130 among a sample of 12691 isolates of human origin collected from January 2006 until June 2011. MRSA CC130 grew insufficiently on chromogernic agar plates for detection of MRSA; the agglutination test for presence of PBP2a was negative. We...

2015
Feng Li Yonghong Xie Lianlian Zhu Li Jiang Xinsheng Chen Baihan Pan Zhengmiao Deng

Both competition and burial are important factors that influence plant growth and structuring plant communities. Competition intensity may decline with increased burial stress. However, experimental evidence is scarce. The aim of this study was to elucidate the role of burial stress in influencing plant competition by investigating biomass accumulation, biomass allocation, and clonal growth per...

Journal: :Molecules 2023

Diabetic foot infection (DFI) is a common complication in diabetes patients, with infections being the leading cause of amputations. Staphylococcus aureus frequently found diabetic infections, which methicillin-resistant (MRSA) has become major clinical and epidemiological challenge. Since MRSA strains are resistant to most β-lactam antibiotics, also partially other treatment difficult costly. ...

ژورنال: دامپزشکی 2017

هدف از این مطالعه بررسی حضور برخی ژن‌های مهم در ارتباط با حدت در باکتری‌های استافیلوکوکوس اورئوس جدا شده از موارد ورم پستان بالینی و تحت بالینی و بررسی ارتباط این ژن‌ها با میزان (Somatic Cell Count (SCC یا شمارش سلول‌های بدنی به عنوان یک شاخص التهابی در بافت پستان بود. برای این منظور حضور شش ژن مهم حدت hla ،agrIII ،SpaA ،coa ،clfA و hlb به ترتیب مربوط به عامل توده‌ای‌کننده، کواگولاز، ناحیه X کد...

Journal: :iranian journal of pathology 2015
abdolmajid ghasemian shahin najar peerayeh bita bakhshi mohsen mirzaee

background:isolates of staphylococcus aureus express a myriad of adhesive surface proteins that play important role in colonization of the bacteria on nasal and skin surfaces, beginning the process of pathogenesis. the aim of this study was to screen several of the microbial surface components recognizing adhesive matrix molecules (mscramms) genes among the isolate of s. aureus from hospitalize...

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