background: although heterotopic gestation is common in assisted reproductive techniques, it is very rare in natural conception and clomiphene induced pregnancy. diagnosis and appropriate intervention of heterotopic pregnancy requires a high index of suspicious. case: in this paper a case of heterotopic pregnancy in a 30-year old woman with hemoperitoneum from ruptured tubal pregnancy with live...

objective: to determine the efficacy of ovarian drilling in pco patients who failed to achieve pregnancy with medical treatment. methods and main results: 75 patients with a diagnosis of pco of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. the other methods like bromocriptin, gonadotropins, gnrh -a and metformin had been given to these patie...

This paper presented a 28-year-old female with systemic sclerosis who developed scleroderma renal crisis and ovarian hyperstimulation syndrome following clomiphene administration. Urgent therapy including angiotensin-converting enzyme (ACE) inhibitors and supportive care resulted in regression and eventually resolution of all the clinical and laboratory symptoms. Although scleroderma renal cris...

■ EVIDENCE-BASED ANSWER Short-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCT]). Metformin also decreases menstrual irregularities (SOR: B, extrapolated from a systematic review). When added to clomiphene, metformin increases ovulatio...

BACKGROUND Laparoscopic electrocautery has been put forward as the treatment of choice in women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS). In order to make an informed treatment decision it would be helpful if we could identify women with PCOS with a high probability of treatment failure following electrocautery of the ovaries. METHODS Eighty-three women with CC-...

clomiphene critrate is an effective and safe treatment for anovulation, but in some cases resistance occurs. to evaluate the efficacy of dexamethasone in resistant anovulatory normal dehydroepiandrosterone patients, we prospectively studied 57 infertile resistant anovulatory women. each woman received 100 mg daily clomiphene critrate from cycle days 3-7 and 0.5 mg dexamethasone from cycle days ...

Objective: To investigate the effect of adding metformin to clomiphene citrate (CC) in polycystic ovarian syndrome (PCOS) patients with acanthosis nigricans (AN) who were previously not responding to CC. Material and Methods: A double blinded randomized controlled trial (NCT02562664) included 66 PCOS women with acanthosis nigricans who were CC resistant (at least 3 months). Day 3 follicle stimu...