نتایج جستجو برای: closed in vitro dissolution test method
تعداد نتایج: 17333692 فیلتر نتایج به سال:
The present work deals with the comparison of in vitro dissolution profiles of fenofibrate liquisolid tablet formulations with those of marketed fenofibrate tablets, and the application of statistical methods to evaluate each method for its usefulness. The methods used to study dissolution profile comparison include Model independent method (Similarity factor, f2); Model dependent methods (Zero...
in iran we already use laminate tubes only in cosmetics industry. laminate tube manufacturers via using the most modern technology of the world, faced with the laminate tube market being saturated in cosmetics industry for packaging the cosmetic creams and toothpaste. but considering the great food market and therefore laminate tube features such as beautiful packaging, ease of use for the fina...
The development of a meaningful dissolution procedure for drug products with limited water solubility has been a challenge to both the pharmaceutical industry and the agencies that regulate them. These challenges include developing and validating the test methods, ensuring that methods are appropriately discriminatory, and addressing the potential for an in vivo–in vitro correlation (IVIVC). Di...
in the present work, a simple and sensitive method was developed for determination of morphine and heroin using gold nanoparticles as resonance rayleigh scattering (rrs) and colorimetric technique’s probe. synthesized gold nanoparticles by sodium citrate reduction method have a negative charge layer on their surfaces because of self-assembled citrate anions on their surface. binding of morphin...
background : mechanical ventilation is used for some infants in neonatal intensive care units (nicu) due to many physiological and clinical causes. since these patients have endotracheal tubes, cleaning and keeping the airways open through suctioning should be done to increase oxygenation. this study aimed to evaluate effect of open and closed suctioning methods on respiratory parameters of inf...
Objective: The objective of the present investigation was to improve dissolution characteristics of EZE, which might offer improved bioavailability. Method: The solid dispersion of Ezetimibe was prepared by Solvent evaporation method by using 1:1, 1:2 and 1:3 ratios of drug and polymers (PVP K-30, Sodium starch glycolate). The tablets were prepared by direct compression method. The compressed t...
Veterinary vaccines must be safe, pure, potent, and effective. Potency tests help ensure that each consistently manufactured batch of vaccine provides a level of protection as determined in the original efficacy study throughout the products shelf life. Currently approved assays range from host animal vaccination and challenge to the quantification of specific protective antigens using in vitro...
Glipizide has been found to form inclusion complexes with β-cyclodextrin (β-CD) in solution and in solid state. The present study was undertaken to determine a suitable method for scaling up glipizide-β-CD inclusion complex formation and to evaluate the effect of some parameters on the efficiency of complexation. The solid inclusion complexes of glipizide and β-CD were prepared at a molar...
Objective: The present research is focused on developing flurbiprofen colon-specific tablets based on timed release and pH-sensitivity. Methods and Material: This study is designed to study the effect of eudragit coating on the drug release from hydroxypropyl methylcellulose matrix to achieve the colon-specific release. Hydroxypropyl methylcellulose matrix tablets were prepared by wet granulati...
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