background: holothuroids (sea cucumbers) are members of the phylum echinodermata, which produce saponins. saponins exhibit a wide spectrum of pharmacological and biological activities. in this study, we isolated the crude saponins from the body wall of the dominant iranian species of sea cucumber, holothuria leucospilota (h. leucospilota). the purpose of this study was to confirm the presence o...

background: alpinia galanga l. belonging to the family zingiberaceae is widely grown in the state of kerala, india. they are effective antioxidant and free radical scavenger under both in vitro and in vivo condition. the efficacy of the isolated flavonoids in conferring protection from radiation induced damages to genomic dna was studied. materials and methods: the bioflavonoids, galangin and k...

Endophytic fungi inside a plant can degrade portion of lignin and cellulose. Penicillium is one the industrial microorganisms with advantage producing enzymes complete enzyme system that be secreted into extracellular space. The natural evolution ancient tree species from special geographic environments to screen out cellulase-producing strains excellent characteristics provides promising direc...

Cellulases are enzymes used in the hydrolysis of lignocellulosic residues for second-generation (2G) bioethanol production, low availability market, and high-cost impacts 40% total cost 2G production. Therefore, it is necessary to look sustainable alternatives its mainly produced by Aspergillus niger, their activity can be affected nitrogen concentration, use surfactants, carbon source, among o...

Bioconversion, particularly enzymatic hydrolysis of cellulosic materials to useful products has great potential and is being actively investigated [l-31. Biotechnological utilization of cellulose requires a very efficient cellulolytic enzyme system active on native cellulose. Cellulases are nulticomponent enzyme systems in which the synergistic action of endoglucanase, exoglucanase and Betagluc...

background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...

a multiple colorimetric assay has been introduced to evaluate the proliferation and determination of survival fraction (sf) of irradiated cells. the estimation of sf based on the cell‑growth curve information is the major advantage of this assay. in this study, the utility of multiple‑mts assay for the sf estimation of irradiated ht‑29 colon cancer cells, which were plated before irradiation, w...