CNS: central nervous system INTRODUCTION Haberland syndrome is characterized by diverse malformations affecting the ecto-mesodermal tissues (the central nervous system, the eye, and the skin). The most prominent anomalies include a hairless fatty tissue nevus of the scalp (nevus psiloliparus) and ocular choristomas. In addition, several central nervous system (CNS) anomalies have been described...

BACKGROUND Congenital anomalies are one of the main causes of morbidity and mortality among infants. The involvement of the central nervous system (CNS) occurs in 21% of cases. OBJECTIVE To identify incidence of CNS malformations and associated factors in newborns at a Terciary Hospital of Porto Alegre. METHOD Case-control study conducted between 2000 and 2005 based on the Latin American Co...

BACKGROUND AND PURPOSE Although it is generally accepted that developmental venous anomalies (DVAs) are benign vascular malformations, over the past years, we have seen patients with symptomatic DVAs. Therefore, we performed a retrospective study and a literature study to review how, when, and why DVAs can become clinically significant. METHODS Charts and angiographic films of 17 patients wit...

Here we report a tooth of a large archosauriform from the Upper Triassic of New Mexico, USA that displays developmental anomalies of carina formation. This tooth has two supernumerary carinae, both on the lingual side of the tooth. Previously, carina anomalies of this sort were primarily known from theropod dinosaurs, but always from the labial surface. Integrating this specimen into a reassess...

Clinic of Diagnostics and Prevention of Developmental Anomalies of Masticatory Apparatus in Children, Department of Oral Surgery of Poznan University of Medical Sciences Head: Aneta Olszewska M.D., PhD Laboratory of Developmental Facial Anomalies, Department of Oral Surgery of Poznan University of Medical Sciences Head: Barbara Biedziak, M.D., PhD Department of Oral Surgery of Poznan University...

OBJECTIVES Venous angiomas, or developmental venous anomalies (DVAs), represent the most often occurring cerebral vascular malformation. The clinical significance of a DVA is, however, at present unclear. METHODS A retrospective analysis was carried out on two series of consecutive cranial MRIs performed between January 1990 and August 1996 in a university department of neuroradiology and in ...

A condensed review of the morphogenetic mechanisms of facial fabrication, providing insights into developmental anomalies of clinical concern. Genetics, epigenetics and regulation of molecular, cellular, tissue and organ formation are being elucidated in normal and dysmorphological patterns. The pathogenesis of craniosynostosis is related to fibroblast growth factor expression. Analysis of a 28...

Birth defects occur in nearly 5% of all live births and are the major cause of infant mortality and morbidity. Despite the recent progress in molecular and developmental biology, the underlying genetic etiology of most congenital anomalies remains unknown. Heterozygous deletion of the 22q11.2 locus results in the most common human genetic deletion syndrome, known as DiGeorge syndrome, and has s...

OBJECTIVE Developmental venous anomalies (DVAs) are benign anatomic variations; therefore, they are usually discovered incidentally. The aim of this article was to describe radiological findings of DVAs. METHODS A retrospective search for DVAs of the brain was performed in 1899 patients who had undergone magnetic resonance imaging (MRI) with contrast enhancement between January 1, 2005 and Ap...