mostasis and inflammation are closely related processes. It is recognized that the activation of hemostasis fosters, to a certain extent, inflammation and that inflammation, in turn, activates the hemostasis system. These interrelationships are best illustrated in sepsis, were microorganisms or their release products, most notably cytokines, causing inflammation, activate the hemostasis system....

Systemic inflammation co-activates coagulation, which unchecked culminates in a lethal syndrome of multi-organ microvascular thrombosis known as disseminated intravascular coagulation (DIC). We studied an endotoxin-induced inflammatory state in rats to identify biomarkers of hemostatic imbalance favoring hypercoagulability. Intraperitoneal injection of LPS at 15 mg/kg body weight resulted in pe...

The present study estimates the effect of rivaroxaban on preventing deep vein thrombosis (DVT) in aged diabetics with femoral neck fractures after hip replacement. Our study consisted of 236 aged diabetics with femoral neck fractures, which were divided into the rivaroxaban and control groups. Reaction time (R time), clot formation time (K time), α angle (α), maximum amplitude (MA), clot elasti...

Background: Hemophilia B is a bleeding disorder with a recessive X-linked inheritance pattern, in which the infected individuals have low levels of factor IX in their plasma. Affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor IX. In order to prevent these episodes and to control bleeding, they should use coagulation factor concen...

the purpose of this study is to investigate the performance and efficiency of moringa seeds from different sources on turbidity. a protein analysis test was done for each source; then two different methods of extraction were compared to examine the coagulation activity for the moringa's active ingredient. the results of sodium chloride (naci) extraction in comparison to distilled water ext...

Mastitis is one of the most prevalent diseases in dairy cattle and cause considerable economic losses. Alongside somatic cell count (SCC), differential (DSCC) has been recently introduced as a new indicator intramammary infection. The DSCC expressed or proportion (%) polymorphonuclear neutrophils plus lymphocytes (PMN-LYM) milk cells. These numbers are complemented to total 100 by macrophages (...

objective(s): haemostasis prevents blood loss following vascular injury. it depends on the unique concert of events involving platelets and specific blood proteins, known as coagulation factors. the clotting system requires precise regulation and coordinated reactions to maintain the integrity of the vasculature. clotting insufficiency mostly occurs due to genetically inherited coagulation fact...

background: type 2 diabetic mellitus patients are amongst the most susceptible groups to vascular abnormalities, which predominantly lead to myocardial disease. the hypercoagulable state has been widely studied by researchers as being the major suspicious mechanism facilitating the consecutive chain of molecular events leading to these complications. however, there is no consensus on the defini...

background: hemophilia b is a bleeding disorder with a recessive x-linked inheritance pattern, in which the infected individuals have low levels of factor ix in their plasma. affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor ix. in order to prevent these episodes and to control bleeding, they should use coagulation factor concen...