PURPOSE Precise and reproducible hippocampus outlining is important to quantify hippocampal atrophy caused by neurodegenerative diseases and to spare the hippocampus in whole brain radiation therapy when performing prophylactic cranial irradiation or treating brain metastases. This study aimed to quantify systematic differences between methods by comparing regional volume and outline reproducib...

The role of radiation therapy in the primary management of small cell lung cancer is very much a matter of current debate. Its value in palliative treatment is unquestioned. Disappointment in the apparent inability to demonstrate improvement in survival in some randomized studies as a result of locoregional radiotherapy and prophylactic cranial irradiation may be due to the use of inappropriate...

background: alzheimer's disease is the most common form of dementia which is still difficult to be differentiated from other types of brain disorders. moreover, mild cognitive impairment refers to the presence of cognitive impairments that is not severe enough to meet the criteria of alzheimer's, and its diagnosis in early stages is so critical. there is currently no distinct method available f...

hospital for evaluation of a four-year history of progressive cognitive im pairment, irritable affect, gait impairment and incontinence. Thirty years earlier, she had undergone surgery and whole-brain radiotherapy (50 Gy in 25 fractions) for a right frontal oligodendroglioma. Her neurologic examination showed paratonia, primitive reflexes, hyperreflexia and difficulty initiating gait, despite p...

BACKGROUND The purpose of the study was to determine the prevalence of metabolic syndrome, growth hormone deficiency, and cardiovascular risk factors among adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with or without cranial irradiation. METHODS Follow-up was undertaken of 75 randomly selected long-term childhood ALL survivors. Testing included fasting insulin, gluc...

Improved treatment for acute lymphoblastic leukemia (ALL) has virtually eliminated testicular relapse. However, the control of central nervous system (CNS) leukemia remains a therapeutic challenge in childhood ALL, partly because of the late complications arising from cranial irradiation. In most current pediatric protocols, cranial irradiation (12 to 18 Gy) is given to 5% to 25% of patients--t...

By combining three series of Scandinavian patients, we were able to compare the late testicular sequelae in 41 adult males whose therapy had included chemotherapy alone or chemotherapy with cranial irradiation without other radiotherapy for ALL in childhood. In multivariate analysis, cranial irradiation was associated with a decrease of 5.7 (95% confidence limits 1.5-9.9) cm (P = 0.010) in heig...

Objectives: Cognitive emotion regulation plays an important role in the emotional intelligence of students with hearing impairment. The present study was conducted to determine the effect of cognitive emotion regulation on emotional intelligence in students with hearing impairment.  Methods: The present study was a quasi-experimental research with pre-test-post-test and control group design. T...