نتایج جستجو برای: cold agglutinin disease
تعداد نتایج: 1591048 فیلتر نتایج به سال:
The cold agglutinin from the albumin gland of the snail Achatina fulica was purified to homogeneity by using sheep gastric mucin-Sepharose 4B as affinity column followed by gel filtration on Bio-Gel P-300. The homogeneity was checked by alkaline gel electrophoresis, immunodiffusion and immunoelectrophoresis. The purified cold agglutinin is a glycoprotein of native M2 220,000 consisting of three...
Phenytoin hypersensitivity syndrome (PHS) is a rare delayed hypersensitivity reaction which occurs following exposure to phenytoin sodium. Pulmonary involvement is uncommonly described. Herein is reported the first case of histopathologic bronchiolitis obliterans organizing pneumonia (BOOP) found on open-lung biopsy in a patient with severe PHS. New onset, clinically significant, cold agglutini...
MINI REVIEW – Drs. Virginia Yao, Renata Pasqualini, and colleagues explore “zip codes” for targeted drug design. PERSPECTIVE – Dr. W. Keith Hoots discusses cross-cutting science at NHLBI’s Division of Blood Diseases and Resources. ASK THE HEMATOLOGIST – Dr. Sigbjorn Berentsen describes the management of primary cold agglutinin disease. CLINICAL TRIALS CORNER – Dr. Theresa Coetzer summarizes the...
Introduction Microscopic polyangitiis is characterized by anti-neutrophil cytoplasmic antibodies (ANCA) and small vessel vasculitis. The diseases usually respond to cyclophosphamide (Cyc) but some patients are therapy resistant. Rituximab (RIT) is a chimeric antibody to CD20 causing lysis of B-lymphocytes and used for treatment of lymphomas. RIT has also been successfully used in patients with ...
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