The antigens reacting with cold-aggluantigen and antibody were not able to tinin antibodies and present in the red react at 37#{176}Cwhen the antigen was cell membranes of human red cells were present in the intact cell, after solubilizafound in the water-phase when the tion, antigen and antibody reacted washed membranes were extracted with equally well at 37#{176}Cand at 0#{176}C. The n-butano...

1. The sera of 80 per cent of the rabbits intravenously inoculated with fixed amounts of heat-killed pneumococci contained agglutinins and all showed protective antibodies. 2. The sera of 60 per cent of the intraperitoneally inoculated rabbits contained agglutinins and all showed protective antibodies. 3. The sera of 33 per cent of the intramuscularly inoculated rabbits contained agglutinins an...

Fertilization in Chlamydomonas reinhardtii is initiated when gametes of opposite mating types adhere to each other via adhesion molecules (agglutinins) on their flagella. Adhesion leads to loss of active agglutinins from the flagella and recruitment of new agglutinins from a pool associated with the cell body. We have been interested in determining the precise cellular location of the pool and ...

We report a 25-year-old man presenting with high fever, dyspnoea and somnolence. The presence of severe diffuse interstitial pneumonia with extrapulmonary symptoms, such as myositis and subclinical haemolysis, strongly suggested an infection by Mycoplasma pneumoniae. This diagnosis was supported by high titres of cold agglutinins and a positive Coombs test, and directly confirmed by specific Ig...

The agglutinins present in the seeds of Abrus precatorius and Ricinus communis have been separated from the toxins, abrin and ricin, and extensively purified. The procedure involves ion exchange chromatography on DEAEand CMcellulose columns, affinity chromatography on Sepharose 4B columns, and sucrose gradient centrifugation. The purified agglutinins which possessed almost no toxic activity wer...

Acute haemolytic anaemia associated with high titre cold agglutinins is an uncommon complication of primary atypical pneumonia. The first description of a case appears in a paper of Clough and Richter4 recording their observations on the haemagglutinins in a patient with bronchopneumonia. In the British literature Besterman and Brigden2 first reported a case and in surveying the literature foun...

In the preceding paper ( 1), there was presented a summary of the maximum titers of cold agglutinins found in 1069 cases of a variety of conditions, including the various infections of the respiratory tract that are commonly encountered in this vicinity. Significant titers (in dilutions greater than 20) were obtained only in cases of primary atypical pneumonia of unknown etiology,' and in a few...