The first-hitting-time based model conceptualizes a random process for subjects’ latent health status. time-to-event outcome is modeled as the first hitting time of to pre-specified threshold. Threshold regression with linear predictors has numerous benefits in causal survival analysis, such estimators’ collapsibility. We propose neural network extension threshold model. With flexibility networ...

INTRODUCTION Intravascular volume status is an important clinical consideration in the management of the critically ill. Point-of-care ultrasonography (POCUS) has gained popularity as a non-invasive means of intravascular volume assessment via examination of the inferior vena cava (IVC). However, there are limited data comparing different acquisition techniques for IVC measurement by POCUS. The...

BACKGROUND This study investigated the effect of varying concentrations of propofol on upper airway collapsibility and the mechanisms responsible for it. METHODS Upper airway collapsibility was determined from pressure-flow relations at three concentrations of propofol anesthesia (effect site concentration = 2.5, 4.0, and 6.0 mug/ml) in 12 subjects spontaneously breathing on continuous positi...

Idiopathic intracranial hypertension (IIH) is a syndrome of unknown cause characterized by elevated intracranial pressure (ICP). While imaging often reveals a stenosis of the transverse sinuses, the role of this feature in IIH has been in dispute. Many patients with chronic daily headache have been found to actually be suffering from a milder form of IIH without papilledema (IIHWOP). These pati...

Objective: Ultrasound assessment of inferior vena cava (IVC) collapsibility is performed to determine the volume status critically ill patients. We propose a new acoustic window for visualizing vein in prone patient. Case Presentation: A healthy volunteer took part study. The study protocol includes two stages: 1) performing magnetic resonance imaging (MRI) examination projection certain IVC ar...

Loess is a kind of special sediment with pore structure and rich carbonate in its composition. Due to the characteristics composition, most loess has collapsibility. There are resources distributed northwest area China. With improvement traffic network west area, use as roadbed gradually increasing. Therefore, during construction process, engineering problems encountered by also increased, whic...

Instillation of surfactant into the pharyngeal lumen reduces the pressure required to reopen an occluded airway, and decreases the apnoea/hypopnoea index (AHI). The authors hypothesised that surfactant also reduces the sleep-related increase in pharyngeal resistance. To test this hypothesis two single blind, crossover, placebo-controlled studies were performed. In protocol A seven male, asympto...

BACKGROUND A study was undertaken to examine the expiratory flow response to a negative pressure (NEP) applied at the airway in patients with no abnormalities of the intrathoracic airway but suffering from the obstructive sleep apnoea syndrome (OSAS). METHODS Nineteen patients with OSAS with normal spirometric values were studied. NEP of -5 cm H(2)O and -10 cm H(2)O was applied to the mouth w...

Taking loess as the research object, influence of cement content on mechanical properties was studied. Firstly, basic physical parameters were obtained through laboratory index test, and improved by using Portland cement. Secondly, under different incorporation ratios (3%, 5%, 7%, 9%), heavy compaction test liquid-plastic limit carried out respectively to obtain cement-improved loess. Finally, ...