Abstract The optimization of cargo loading and transportation are two highly considered problems (namely “3L-CVRP”). combination both has attracted increasing interest in the past decades. Hereby, 2D or 3D items have to be transported from one depot a given set customers using homogeneous fleet vehicles. Each route must provided with feasible packing plan taking various constraints into account...

Early tendon healing can be stimulated by mechanical loading and inhibited by cyclooxygenase (COX) inhibitors (nonsteroidal anti-inflammatory drugs). Therefore, we investigated if impairment of tendon healing by a COX-2 inhibitor (parecoxib) is related to loading. Because loading might infer microdamage, which also stimulates healing, we also investigated if this effect is inhibited by parecoxi...

Strain-hardening cement-based composites (SHCC) are a novel class of fiber-reinforced concretes which exhibit high tensile strain capacity prior to failure localization. Although the behavior SHCC has been matter study in numerous research works, these under other loading modes scarcely investigated. The article at hand addresses mechanical two types normal-strength subject uniaxial tension, to...

In current design practice, spatiotemporally varying wind loads on buildings are modeled as equivalent static wind loads. This loading description serves as pivotal information for estimating response under the combined action of wind and other loads. This paper presents a framework for evaluating the equivalent static wind load for any given peak response of buildings with uncoupled responses ...

Loading of nutrients from terrestrial ecosystems strongly influences the productivity and biogeochemistry of aquatic ecosystems. Human activities can supplement and even dominate nutrient loading to many lakes, particularly in agricultural and urbanized settings. For lakes in more remote regions such as the Adirondack Mountains of New York, N deposition represents the primary potential anthropo...

PURPOSE To report on the effect of immediate implant loading with fixed prostheses compared to early and conventional loading on implant and prosthesis survival, failure, and complications. MATERIALS AND METHODS An electronic and manual search was conducted to identify randomized controlled clinical trials (RCTs) as well as prospective and retrospective studies involving rough surface implant...

  Purpose: Blast-induced traumatic brain injury (bTBI) is one of the causes of death or permanent   invalidity which can occur unexpectedly in both military and civilian populations. This study   set out to conduct a combined Eulerian-Lagrangian computational analysis of the interaction   between a single planar blast wave and a human head in order to assess the extent of intracranial   shock w...

one of the methods for the improvement of soil against the tensile stresses is using the artificial supplements in soil such as metal belts or nets, polymer materials and natural fibers. technically this method is called the reinforced of soil.  when a pavement is located on soft soil, great deformations can occur as a result of the crossing of traffic load in superstructure layers of the body....

Ultra-thin diamond-like carbon (DLC) coatings are used in precision engineering applications, such as magnetic storage devices, to protect intricate structures from wear and corrosion. A DLC coating typically consists of hard amorphous carbon in combination with an interlayer such as silicon (Si), to improve adhesion to the substrate material. Deformation and delamination of these coatings, eve...