Several investigators who have had a large experience with the complement fixation test for lues have called attention to the development in sera of anticomplementary bodies which cause inhibition of hemolysis in both the antigen and control tubes, and they have found that in most instances this property of the serum is lost after heating it for half an hour at 560 C. In some instances, however...

Case 1 The following was received from an ophthalmologist concerning a 46-year-old patient: "He has left hyalitis, which is secondary to cyclitis. The gonococcal complement-fixation test was weakly positive. I have told the patient the result of the blood test." The patient's wife had left him after hearing the diagnosis but later returned to him. So many positive gonococcal complement-fixation...

A simplified enzyme-linked immunosorbent assay (ELISA) which utilized commercially available reagents was developed for respiratory syncytial virus (RSV)-specific immunoglobulin G. An analysis of the inherent variation of the assay allowed the setting of strict criteria for determining a significant change in RSV antibodies. The ELISA was more sensitive than the standard complement fixation or ...

1. Two principal types of gonococci may be recognized by suitable immunological tests; e. g., agglutination and complement fixation. These two types correspond to the adult and infant types of infection with the gonococcus, seen clinically. 2. On the basis of the immunological reactions of agglutination and complement fixation the strains of gonococci isolated from three cases of ophthalmia are...

THE WASSERMANN REACTION (C.L.W.R.) The original Wassermann test was a complement-fixation test which used as the antigen treponema from the liver of a syphilitic stillborn child (Bordet, Gengo^ Wassermann, 1906). Although the true Wassermann test is no longer carried out it15 not uncommon for the term to be used as a generic expression for any complement' fixation test using heart extract as th...

The counterimmunoelectrophoresis (CIE) technique was developed as a diagnostic procedure for ram epididymitis caused by Brucella ovis. CIE test results with sera from naturally and experimentally infected male sheep compared favorably with those obtained by gel diffusion and complement fixation employing the same B. ovis surface R antigen. The main advantage of CIE over gel diffusion consists i...

Complement fixation (CF) and hematological studies were performed on 517 cows living in normal conditions in different geographical areas of France. The animals belonged to three different categories: (1) multiple or single case herds, in which lymphosarcomas had been detected in the past five years. (2) Leukemia free herds of high risk regions. (3) Leukemia free and apparently unexposed herds....

BACKGROUND The internationally mandatory complement fixation test (CFT) for testing of equine sera for the absence of glanders has repeatedly led to discrepant results. Not only do "false positive" sera pose a problem for the diagnostician and the animal health authorities but they can also result in significant financial losses for the animal owners.Due to the very low prevalence of glanders i...