After traumatic spinal cord injury, grossly injured blood vessels leak blood and fluid into the parenchyma, leading to a large cystic cavity. Fibroblast growth factor-2 (FGF2) can reduce immediate vasoconstriction of vessels in the tissue surrounding the primary injury and promote angiogenesis. A localized delivery system would both achieve restricted delivery of FGF2 to the spinal cord and lim...

OBJECTIVE This analysis was undertaken to determine the composite incidence of cumulative adverse events (death, reinfarction, disabling stroke, and target vessel revascularization) at the end of the first year after acute myocardial infarction, in diabetic patients who underwent coronary stenting or primary coronary balloon angioplasty. METHODS From the STENT PAMI trial, we analyzed the 6-mo...

localizing the optic disc (od) in retinal fundus images is of critical importance, since it is very similar to hard exudates (found in pathology) in color and brightness. because of the importance of od localization in clinical applications, many techniques have been developed. in this paper, we present the results obtained from two methods, correlation and least square, to approximate the opti...

coronary artery anomalies are rare, with their incidence varying from 1 to 5%. angiography is a commonly used modality for the assessment of coronary artery anomalies. based on previous reports, a majority of coronary artery anomalies are of origin or distribution, with separate ostia of the left anterior descending artery and left circumflex artery. coronary artery anomalies may cause myocardi...

anomalous origin of the left coronary artery from the pulmonary artery (alcapa) is a rare congenital cardiac malformation. we report three cases of alcapa who survived to adulthood. the first case was a 51-year-old woman who complained of typical chest pain that was diagnosed with alcapa using cardiac catheterization and coronary computed tomographic angiography (cta). the second case was a 30-...

The use of fibre reinforced composite materials is one method by which the lightweighting rail vehicles can be achieved. However, issue impact damage, amongst other challenges, limits their safety certification. This accentuated high levels loading a vehicle may subjected to during service. paper addresses significance pre-tension on large structures, specifically for redesign pressure vessel f...

Composite overwrapped pressure vessels are typically used to store gases such as hydrogen under high pressure. Internal damage due an impact may reduce the strength of vessel, through which internal at failure, so-called burst pressure, drop significantly. Advanced material models can be predict what extend a vessel decreases. However, current studies do not consider complex mechanisms that cau...

The goal of this experimental study is to manufacture a bolted GFRP flange connection for composite pipes with high strength and performance. A mould was designed manufactured, which ensures the quality materials controls its surface grade. Based on ASME Boiler Pressure Vessel Code, Section X, fabricated using biaxial glass fibre braid polyester resin in vacuum infusion process. In addition, ma...

Treatment of in-stent restenosis (ISR) is still a technical challenge for interventional cardiologists. Several studies have demonstrated that treating drug-eluting stent (DES) ISR is even more challenging because of the unfavorable substrate of DES ISR because of the presence of resistant stent underexpansion or neoatherosclerosis that have been shown to be associated with poorer clinical and ...

CONTEXT The Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) trial showed the efficacy of adjunctive, double-bolus eptifibatide therapy in reducing ischemic complications of nonurgent coronary stent implantation at 48 hours and at 30 days. OBJECTIVE To determine whether the beneficial effects of eptifibatide persist at 6 months after treatment. DESIGN ...