Following initial observations of marked effects of nicotine self-medication in a patient with obsessive-compulsive disorder (OCD), another four OCD patients were treated with nicotine for eight weeks in an open label fashion. Patients fulfilling DSM-IV criteria for OCD and with initial Yale-Brown Obsessive-Compulsive Scale (YBOCS) score>15 were included in the study. The patients were scored w...

The etiopathogenesis of obsessive-compulsive disorder (OCD) remains elusive. Clinical observation of the elevated frequency of obsessive-compulsive symptoms in patients with rheumatic fever, a post-streptococcal autoimmune disease, prompted the study of immune parameters in OCD. Anti-basal ganglia antibodies have been described in a subset of OCD patients. The assessment of circulating cytokine...

Research on the relationship between personality factors and obsessive-compulsive disorder (OCD) has proved difficult to interpret due to conceptual problems including a lack of consensus on the model of personality employed as a framework as well as a failure to consider the clinical heterogeneity of the disorder. The aim of this study was to examine the dimensional personality profile associa...

This narrative review is organized around the primary symptoms of obsessive compulsive disorder (OCD) including physical and cognitive effectiveness behavior therapy (CBT) in reducing these youth with an OCD diagnosis. These are followed by sections on comorbidities anxiety depression, effective delivery CBT via both internet in-person, greater versus pharmacotherapy, use alternative therapies ...

objective: recent studies have emphasized the important role of cognitive beliefs in etiology and ‎maintenance of obsessive-compulsive disorder (ocd). ocd has different subtypes, but the ‎specific role of cognitive beliefs in ocd symptomatology is not clear. the aim of the current ‎study was to determine whether the cognitive factors proposed by obsessive compulsive ‎cognitions working group (o...

Cognitive models of obsessive-compulsive disorder (OCD) posit that specific kinds of dysfunctional beliefs (e.g., pertaining to responsibility and the significance of intrusive thoughts) underlie the development of this disorder. The present study was designed to prospectively evaluate whether dysfunctional beliefs thought to underlie OCD act as a specific vulnerability factor in the pathogenes...

Recent acceptance that obsessive-compulsive disorder (OCD) represents a heterogeneous phenomenon has underscored the need for dimensional approaches to this disorder. However little is known about the relation between neuropsychological functions and symptom dimensions. The purpose of this study was to identify the cognitive deficits correlated with specific symptom dimensions. Thirteen categor...

Inferential confusion has been defined as a confusion between reality and possibility, where the person with Obsessive–Compulsive Disorder (OCD) persists in his/her obsessional belief despite sense information to the contrary. The current study investigates whether inferential confusion is associated with treatment outcome in an OCD sample receiving cognitive–behavioral therapy (CBT). Results i...

A case of hypersexual behavior occurring in association with obsessive-compulsive disorder (OCD) is described. This patient had non–paraphilic heterosexual multiple partner behavior or sexual addiction. The patient also exhibited nonsexual obsessions and compulsions diagnostic of obsessive-compulsive disorder. The case is presented for its clinical interest, because sexual addiction is rare esp...