Objective: To define the incidence of brain and kidney anomalies in newborns with significant congenital heart disease admitted to the cardiac intensive care unit at Nicklaus Children’s Hospital. Study Design: A retrospective chart review of head and renal ultrasound was studied for newborns who were admitted with significant congenital heart disease to Nicklaus Children’s Hospital cardiac inte...

BACKGROUND Inflammatory bowel disease (IBD) affects people during their prime reproductive years. The thiopurines (6-mercaptopurine and azathioprine), commonly used for induction and maintenance of remission, are U.S. Food and Drug Administration (FDA) pregnancy category D, raising concern for fetal risk. We performed a systematic review and meta-analysis to evaluate the effects of thiopurine e...

Background: Congenital hypothyroidism (CH), as one of the most common congenital endocrine disorders, may be significantly associated with congenital malformations. This study investigates urogenital abnormalities in children with primary CH (PCH). Methods: This case-control study was conducted on 200 children aged three months to 1 year, referred to Amir-Kabir Hospital, Arak, Iran. One hundred...

The aim of this project was to study the possible association between maternal infusion treatments during pregnancy and variables of fetal development as well as the occurrence of congenital abnormalities (CA) in a case-control design. The large population-based data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities (HCCSCA) was evaluated based on the medically recorded...

Echocardiography is often insufficient to evaluate congenital thoracic vascular abnormalities. CT and MRI are excellent imaging modalities for assessment of congenital thoracic vascular anomalies. The main advantages of MRI are absence of radiation exposure and possibility of concomitant flow quantification. The advantages of CT are short examination time, high spatial resolution, possibility o...

Background: Congenital Zika virus (SCZV) infection is associated with a spectrum of severe neurological abnormalities, mainly microcephaly, and central nervous system malformation. In this way, it becomes relevant to know the main alterations that accompany SCZV in Ceará.

CMR is valuable in the evaluation of congenital heart disease (CHD). Traditional flow imaging sequences involve cardiac and respiratory gating, increasing scan time and susceptibility to arrhythmias. We studied a real-time color-flow CMR system for the detection of flow abnormalities in 13 adults with CHD. All 16 congenital flow abnormalities previously detected by echocardiography were visuali...

Background: In many countries, 1% to 3% of newborn infants are conceived by Assisted Reproductive Techniques (ART). Despite the success of ART, there is concern about the risk of congenital malformations among these infants. We report our experience to determine whether use of ART is associated with an increase in major congenital malformations or adverse pregnancy outcomes Materials and Method...

Cervical abnormalities may be congenital or acquired. Congenital anomalies of the cervix are rarely isolated, and more commonly accompany other uterine anomalies. Various imaging tools have been used in the assessment of Mullerian duct anomalies (MDAs). Currently, magnetic resonance imaging (MRI) is the modality of choice for definitive diagnosis and classification of the MDAs. Hysterosalpingog...

Thyroid diseases in children and adolescents include acquired or congenital conditions, including genetic disorders either isolated part of a syndrome. Briefly, we will review the physiology pathophysiology thyroid gland its disorders. The aim this chapter is to describe abnormalities gland.