True cardiac emergencies in children are rare compared with the adult population. Cardiac diseases in infancy and childhood may be acquired or congenital. Acquired cardiac disorders, such as cardiac tamponade, usually evolve acutely, and result in sudden alterations in cardiac physiology that may lead to rapid deterioration. Although 0.8% to 1% of infants have congenital heart disease, most are...

Pregnancy outcomes in patients with congenital heart disease have not been fully assessed in Korea. Forty-nine pregnancies that occurred in 34 women with congenital heart disease who registered at our hospital between September 1995 and April 2006 were reviewed. Spontaneous abortions occurred in two pregnancies at 6+1 and 7 weeks, and another two underwent elective pregnancy termination. One ma...

Cardiac arrhythmias are among the leading causes of mortality. They often arise from alterations in electrophysiological properties cardiac cells and their underlying ionic mechanisms. It is therefore critical to further unravel pathophysiology basis human electrophysiology health disease. In first part this review, current knowledge on differences ion channel expression processes that determin...

introduction: hearing impairment is the most frequent sensorial congenital defect in newborns and has increased to 2–4 cases per 1,000 live births. sensory-neural hearing loss (snhl) accounts for more than 90% of all hearing loss. this disorder is associated with other congenital disorders such as renal, skeletal, ocular, and cardiac disorders. given that congenital heart diseases are life-thre...

BACKGROUND The cardiovascular effects of halogenated anesthetic agents in children with normal hearts have been studied, but data in children with cardiac disease are limited. This study compared the effects of halothane, isoflurane, sevoflurane, and fentanyl-midazolam on systemic and pulmonary hemodynamics and myocardial contractility in patients with congenital heart disease. METHODS Fifty-...

BACKGROUND Inherited deficiency of phosophomannomutase (PMM2) causes a human glycosylation disorder known as Congenital Disorder of Glycosylation Ia. CASE PRESENTATION Herein, we describe a case of congenital disorder of glycosylation Ia, presented with recurrent pericardial effusion and unusual findings of inverted nipples, fat pads, reduced deep-tendon reflexes and multisystem involvement. ...