purpose : to determine the distribution of cataract surgery in iran between 2000 and 2005 methods : in a retrospective study based on files, cataract surgery centers were selected. between 2000 and 2005, one week of each season was selected randomly and all cataract surgery files of the center were studied. the surgeries were analyzed based on type, types of the lenses, intraoperative complicat...

PURPOSE To describe a Jewish family of Libyan ancestry in which autosomal dominant congenital cataract segregates with an apparently balanced reciprocal chromosomal translocation. METHODS Detailed family history and clinical data were recorded. Cytogenetic studies were performed on 13 family members. RESULTS Embryonal cataracts cosegregated through three generations with a balanced chromoso...

Those born with congenital cataracts tend to develop retinal detachments, irrespective of whether or not cataract surgery is undertaken (Malbran and Dodds, i964), although the patient may reach middle age before the retina separates (Shapland, I962). The prospects of curing such detachments are generally regarded as poor (McDonald, I957), and since the literature is devoid of any series giving ...

In Australia in the 1940s, Norman McAlister Gregg observed a connection between pregnant women who contracted the rubella virus, or German measles, and cataract formation in their children's eyes. Gregg published his findings in the 1941 article "Congenital Cataract following German Measles in the Mother" in Transactions of the Ophthalmological Society of Australia. In the article, Gregg analyz...

Presentation and outcome, particularly in terms of development, nursery, and school placement of 55 children with treated congenital cataracts was studied. Results indicate that although most children have satisfactory vision many of their parents would have welcomed more support at the time of the diagnosis, an opportunity to talk to parents of similarly affected children, and further advice o...

BACKGROUND Congenital Cataract Facial Dysmorphism and demyelinating Neuropathy (CCFDN, OMIM 604468) is an autosomal recessive multi-system disorder which was first described in Bulgarian Gypsies in 1999. It is caused by the homozygous founder mutation c.863 + 389C > T in the CTDP1 gene. The syndrome has been described exclusively in patients of Gypsy ancestry. The prevalence of this disorder in...

PURPOSE To report the visual outcomes and complications of congenital cataract surgery with primary intraocular lens implantation in microphthalmic eyes of children younger than 4 years of age. METHODS This retrospective interventional case series included 14 microphthalmic eyes from 10 children who underwent congenital cataract surgery with primary intraocular lens implantation younger than ...

PURPOSE To undertake mutation screening in the connexin 46 (GJA3) gene in seven congenital cataract families of Indian origin. METHODS Seven Indian families with congenital cataract were analyzed by detailed family history and clinical evaluation. Each family had two to five affected members. Mutation screening was carried out in the candidate gene, connexin 46 (GJA3), using bidirectional seq...

PURPOSE To identify the genetic defect associated with autosomal dominant congenital cataract (ADCC) in a Chinese family, in which 11 individuals across four generations are affected with coralliform cataract. METHODS Exome sequencing was performed in two of the ADCC-affected family members to scan for potential genetic defects. Sanger sequencing was used to verify these defects in the whole ...

OBJECTIVES To determine the mode of detection and timing of ophthalmic assessment of a nationally representative group of children with congenital and infantile cataract. DESIGN Cross sectional study. SETTING United Kingdom. SUBJECTS All children born in the United Kingdom and aged 15 years or under in whom congenital or infantile cataract was newly diagnosed between October 1995 and Sept...