Contact lens wear is highly influential on the incidence of ulcerative keratitis worldwide, particularly in developed countries. The association between Acanthamoeba keratitis and contact lens wear is firmly established; it may account for up to 95% of the reported cases. Before the popularisation of soft contact lens wear, Acanthamoeba keratitis was extremely rare. In 2000 it was estimated tha...

1. Wagner S, Conrad F, Bakaraju RC, Fedtke C, Ehrmann K, Holden BA. Power profiles of single vision and multifocal soft contact lenses. Cont Lens Anterior Eye. 2014;38:2--14. 2. Plainis S, Atchison DA, Charman WN. Power profiles of multifocal contact lenses and their interpretation. Optom Vis Sci. 2013;90:1066--1077. 3. Joannes L, Hough T, Hutsebaut X, et al. The reproducibility of a new power ...

The deposition of biological material (biofouling) onto polymeric contact lenses is thought to be a major contributor to lens discomfort and hence discontinuation of wear. We describe a method to characterize lipid deposits directly from worn contact lenses utilizing liquid extraction surface analysis coupled to tandem mass spectrometry (LESA-MS/MS). This technique effected facile and reproduci...

PURPOSE Based on contact lens-induced stromal acidification of the cornea, it has been suggested that the corneal epithelial and endothelial cells also become acidotic during contact lens wear. This alleged acidification may have a role in altered cell appearance and metabolism during contact lens wear. This study investigated the effects of anoxia, carbon dioxide retention, and contact lens ga...

LENS implants may be classified according to the position of the optical part (posterior chamber lens, anterior chamber lens, pupillary lens), the material used (acrylic, silicate glass, quartz, one-piece lens, two-material lens), and the method of fixation (Binkhorst, 1962a, b). As fixation is obtained by contact of the haptic part of the pseudophakos with the ocular tissues, the subsequent st...