purpose: to evaluate corneal thickness changes after soft contact lens (scl) removal in lasik candidates. methods: fifty lasik candidates (100 eyes) with history of daily wear scl for at least 6 months were enrolled in this descriptive study. central corneal thickness was measured by ultrasonic pachymetry immediately after lens removal and then repeated daily at the same time, until the thickne...

purpose: to specify histopathologic features of corneal involvement in a case with xeroderma pigmentosum (xp). case report: a 19-year-old man with a clinical diagnosis of xp presented with bilateral corneal leukoma and decreased visual acuity predominatly in his right eye. penetrating keratoplasty was performed in the right eye due to severe corneal opacity, vascularization and lipid deposition...

The present study investigated the effects of microinjections of acetylcholine (a cholinergic agonist), physostigmine (a cholinesterase inhibitor), atropine (an antagonist of muscarinic cholinergic receptors) and hexamethonium (an antagonist of nicotinic cholinergic receptors) into the parafascicular nucleus of thalamus on the acute corneal nociception in rats. Acute corneal nociception was ind...

purpose: to evaluate the effect of topical phenytoin 1 % on corneal epithelial defects healing in a rabbit model. methods: one eye of 20 albino rabbits in the animal house of al-zahra ophthalmology hospital was studied. a single corneal epithelial defect was created. the rabbits were randomly assigned into two groups (ten animals in each group). after creating a chemical burn in rabbits, one gr...

Skin wounds like scrapes and cuts may be painful, but they usually heal perfectly. Worst case scenario, you may be left with a scar. In contrast, when the brain gets injured, we are often left with disabilities that stay with us for the rest of our lives. What is so different about the brain, and how does it repair itself? Brain cells face unique challenges when they get injured, for example, b...

corneal ulcer is a major cause of blindness throughout the world. when the cornea is injured by foreign particles, there are chances of infection by the organism and development of ulcer. bacterial infection in the cornea is invariably an alteration of the defense mechanism of the outer eye. it is essential to determine the local etiology within a given region when planning a corneal ulcer mana...