PURPOSE To compare visual acuity, total and high order wavefront aberrations (coma, spherical aberration, and other terms of high order aberration), and contrast sensitivity in 105 eyes implanted with 4 different types of intraocular lenses (IOLs) (1 multifocal apodized diffractive IOL and 3 monofocal IOLs). METHODS A prospective study comparing four types of IOLs (Alcon ReSTOR [50 eyes], Alc...

BACKGROUND The purpose of this study was to evaluate the effect of daily administration of mannitol-enriched sodium hyaluronate ophthalmic solution on the corneal optical properties of subjects wearing low Dk hydrogel (etafilcon A) contact lenses (CLs). METHODS Forty-five subjects wearing etafilcon A CLs daily for more than 6 months were recruited into this pilot study. Fifteen of the subject...

PURPOSE To assess the performance and optical limitations of standard, aspheric, and wavefront-customized intraocular lenses (IOLs) using clinically verified pseudophakic eye models. METHODS White light pseudophakic eye models were constructed from physical measurements performed on 46 individual cataract patients and subsequently verified using the clinically measured contrast sensitivity fu...

Acousto-optic deflectors (AODs) arranged in series and driven with linearly chirped frequencies can rapidly focus and tilt optical wavefronts, enabling high-speed 3D random access microscopy. Non-linearly chirped acoustic drive frequencies can also be used to shape the optical wavefront allowing a range of higher-order aberrations to be generated. However, to date, wavefront shaping with AODs h...

It is well accepted that the accommodation system is characterized by steady-state errors in focus. The purpose of this study was to correlate these errors with changes in ocular wavefront aberration and corresponding image quality when accommodating. A wavefront analyzing system, the Complete Ophthalmic Analysis System (COAS), was used in conjunction with a Badal optometer to allow continuous ...

As semiconductor lithography is pushed to smaller dimensions, process yields tend to suffer due to subwavelength topographical imaging effects. Three dimensional or “thick mask” effects result in such things as a pitch dependent best focus and, for alternating phase shift masks (AltPSMs), an intensity imbalance between etched and un-etched features. Corrective mask structures such as the dual t...

In many scientific and medical applications, such as laser systems and microscopes, wavefront-sensor-less (WFSless) adaptive optics (AO) systems are used to improve the laser beam quality or the image resolution by correcting the wavefront aberration in the optical path. The lack of direct wavefront measurement in WFSless AO systems imposes a challenge to achieve efficient aberration correction...

Purpose To determine topographic and aberrometric changes after accelerated cross-linking (ACXL; 18 mW/cm2 for 5 min) as measured with OPD Scan III (Nidek Inc., Tokyo, Japan) and their repeatability in patients with mild and moderate keratoconus (KCN). Methods In this prospective study, 25 eyes with mild KCN [Ksteep = 47.24 ± 3.11 diopter (D)] and 20 moderate cases (Ksteep = 52.86 ± 4.39 D) w...

Measurement of ocular wavefront aberration is becoming a popular clinical technique due to recent technical advances and an increasing awareness of its potential for practical application in the fields of surgical and optical refractive correction. In addition, information about the status of peripheral refraction determined from ocular wavefront aberrations is now being used to monitor the pro...

METHODS: Assuming that cyclotorsion error can be estimated and compensated for with a certain level of uncertainty, we formulate a function to modify the wavefront error in order to minimize the residual aberration magnitudes due to cyclotorsion measurement uncertainty. A modal optimum nomogram factor is computed for minimization of the residual aberration for each Zernike mode. We also calcula...