نتایج جستجو برای: cox models
تعداد نتایج: 943575 فیلتر نتایج به سال:
Page Title 1 Overview − hierarchical models 2 Calf mortality data 3 Hierarchical regression models 4 Hierarchical survival models: general approaches 5 Calf mortality data: multi-level Cox model 6 Methods for hierarchical Cox models 7 Pig lameness data 8 Pig data: hypothesis and first results 9 Pig data: Cox random slope models 10 Pig data: parametric models 11 Proportional hazards revisited 12...
COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R2) of 0.972 and 0.531 for training and test groups, respectively. The quality of the mod...
A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. According to in-vitro COX-1/COX-2 inhibition data, all compounds (6a-g) were selective inhibitors of COX-2 isoenzyme with IC50 values in the highly potent 0.08-0.16 mM range. These results indicated that both potency and selectivity o...
JOSEPH F. Ross, M.D., Edilor
JOSEPH F. Ross, M.D., Editor
JOSEPH F. Ross, M.D., Editor
JOSEPH F. Ross, M.D., Editor
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