نتایج جستجو برای: cox models

تعداد نتایج: 943575  

2015
Henrik Stryhn

Page Title 1 Overview − hierarchical models 2 Calf mortality data 3 Hierarchical regression models 4 Hierarchical survival models: general approaches 5 Calf mortality data: multi-level Cox model 6 Methods for hierarchical Cox models 7 Pig lameness data 8 Pig data: hypothesis and first results 9 Pig data: Cox random slope models 10 Pig data: parametric models 11 Proportional hazards revisited 12...

COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R2) of 0.972 and 0.531 for training and test groups, respectively. The quality of the mod...

A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. According to in-vitro COX-1/COX-2 inhibition data, all compounds (6a-g) were selective inhibitors of COX-2 isoenzyme with IC50 values in the highly potent 0.08-0.16 mM range. These results indicated that both potency and selectivity o...

2005
Helen W. Belding Conrad Maier Robert B. Chodos

JOSEPH F. Ross, M.D., Edilor

2005
Helen W. Belding N. C. Conrad Maier Robert B. Chodos Charles E. Rath Jean P. Soulier

JOSEPH F. Ross, M.D., Editor

2005
Sheila T. Callender Philip F. Wagley

JOSEPH F. Ross, M.D., Editor

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