Citation: Agalou A, Thrapsianiotis M, Angelis A, Papakyriakou A, Skaltsounis A-L, Aligiannis N and Beis D (2018) Identification of Novel Melanin Synthesis Inhibitors From Crataegus pycnoloba Using an in Vivo Zebrafish Phenotypic Assay. Front. Pharmacol. 9:265. doi: 10.3389/fphar.2018.00265 Identification of Novel Melanin Synthesis Inhibitors From Crataegus pycnoloba Using an in Vivo Zebrafish P...

background and objectives: gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...

Spatial distribution of palatable and unpalatable plants can influence the foraging behaviour of herbivores, thereby changing plant-damage probabilities. Moreover, the immediate proximity to certain plants can benefit other plants that grow below them, where toxicity or spines act as a physical barrier or concealment against herbivores. This paper presents the results of a multi-scale experimen...

Bumblebees (Bombus species) are major pollinators of commercial crops and wildflowers but factors affecting their abundance, including causes of recent population declines, remain unclear. Investigating the ecology of species with expanding ranges provides a potentially powerful means of elucidating these factors. Such species may also bring novel pollination services to their new ranges. We th...

Transpiration from a hawthorn (Crataegus monogyna L.) dominated hedgerow in southern England was measured continuously over two growing seasons by the sap flow technique. Accompanying measurements of structural parameters, microclimate and leaf stomatal and boundary layer conductances were used to establish the driving factors of hedgerow transpiration. Observed transpiration rates, reaching pe...

BACKGROUND AND AIMS In the UK, the flowers of fruit-bearing hedgerow plants provide a succession of pollen and nectar for flower-visiting insects for much of the year. The fruits of hedgerow plants are a source of winter food for frugivorous birds on farmland. It is unclear whether recent declines in pollinator populations are likely to threaten fruit-set and hence food supply for birds. The pr...

objective(s):the current study was aimed to determine the bioactive constituents and biological effects of the crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia. materials and methods: oleanolic acid, ursolic acid, quercetin and lupeol concentrations were quantified by hplc. total phenol content and radical scavenging activity of extracts were also meas...

Scolus secretions and hemolymph of caterpillars of Saturnia pyri fed with two different foodplants (Crataegis monogyna, Prunus spinosa) were chemically analyzed and their chemical similarities determined. The secondary-compound patterns obtained for the two body fluids showed no significant differences when compared between the two groups of alternatively fed last-instar larvae. Thus, the compo...

Attractive and repellent properties of many household chemicals may be used to combat synantrophic insects, such as cockroaches. In the natural environment, Shelfordella lateralis (Walker, 1868) (Blattodea, Blattidae) lives in area spanning Central Asia North Africa. Furthermore, tropical subtropical countries, it is common human accomodations. laboratory conditions, we determined reaction cock...