This work was done to evaluate the effect of ethanolic extract Palisota hirsuta on nephrotoxicity induced by carbontetrachloride (CCl4). Biochemical analyses were carried out determine levels creatinine, urea, total protein, chloride, carbonate using assay kits (products Randox Laboratories Crumlin and Teco Diagnostics), sodium, potassium (method Tietz,) malondialdelyde (MDA) level (thiobarbitu...

A new LC-MS/MS method with simple sample extraction and a relatively short period of vancomycin analysis for routine therapeutic drug monitoring was developed and validated. 50μL serum was precipitated using 20μL 33% trichloroacetic acid and 0.5mol/L NH4OH was added to increase pH before analysis. A RP BEH C18, 1.7μm, 2.1×50mm column maintained at 30°C and tobramycin as internal standard were u...

Glomerular filtration rate (GFR) is commonly assessed by measurement of endogenous creatinine clearance (Ccr). Several formulae have been described to calculate Ccr from plasma creatinine. I have evaluated the effectiveness of four formulae in 35 healthy subjects (21M and 14F, 18-34 years) and in 41 patients (24M, 17F, 20-69 years) attending a renal clinic with diminished renal function (serum ...

purpose: to evaluate the effects of silver nanoparticles on some serum parameters in mice. materials and methods: forty mice, including twenty male and twenty female, were randomly divided into eight groups: c1 and c2 (male and female control groups, respectively), t1, t2 and t3 (male treatment groups), t4, t5 and t6 (female treatment groups). after the acclimatization period, the treatment gro...

studies have shown that patients who do not produce donor specific and / or panel reactive anti-hla antibodies have a longer graft survival. the purpose of this study was to evaluate the posttransplant humoral immune response towards hla-class i antigens and the measurement of the serum creatinine levels which are used in monitoring posttransplant function of kidney. serum samples from 132 rena...

The current study aimed to investigate the curative and preventive effect of alcoholic aqueous extract Capparis spinosa leaves on histological structure kidneys some biochemical parameters male rats injected intraperitoneally with lead acetate. Biometrics included urea, creatinine, uric acid total protein levels antioxidants (T-AOX), glutathione (GSH) malondial aldehyde (MDA) assay. 40 laborato...