Saffron (Crocus sativus) stigma tablets were evaluated for short-term safety and tolerability in healthy adult volunteers. The study was a double-blind, placebo-controlled design consisting of a 1 week treatment of saffron tablets. Volunteers were divided into 3 groups of 10 each (5 males and 5 females). Group I received placebo; groups 2 and 3 received 200 and 400mg saffron tablets, respective...

background & aim: saffron (crocus sativus l.) formerly was important in turkey. saffron cultivation has been decreased and it is now only cultivated in three villages in this country. it is triploid and exclusively propagated in a vegetative way by corms. in turkey, saffron is traditionally planted by placing corms in rows randomly without grading or sorting; which results in placement of c...

objective(s): the effect of the extract of crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   materials and methods: ovalbumin (oa) sensitized guinea pigs were given drinking water alone (group s), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6...