Despite widespread use and prospective biomedical applications of copper nanoparticles (Cu NPs), their biosafety issues and kinetics remain unclear. Thus, the aim of this study was to compare the detailed in vivo toxicity of Cu NPs and cupric ions (CuCl2; Cu ions) after a single oral dose. We determined the physicochemical characteristics of Cu NPs, including morphology, hydrodynamic size, zeta...

Copper sulfate is often added to broiler and laying hen diets at prophylactic dosages due to its antimicrobial and growth promoting effects despite reduced P digestibility, whereas P use from other Cu sources is unknown. Therefore, male broiler chicks were fed diets containing 0 or 250 ppm Cu from Cu sulfate (Cu SUL), Cu citrate (Cu CIT), Cu lysinate (Cu LYS), or CuCl from 9 to 22 d of age (8 c...

Spectroscopic methods combined with density functional calculations are used to develop a detailed bonding description of the mu(4)-sulfide bridged tetranuclear Cu(Z) cluster in N(2)O reductase. The ground state of Cu(Z) has the 1Cu(II)/3Cu(I) configuration. The single electron hole dominantly resides on one Cu atom (Cu(I)) and partially delocalizes onto a second Cu atom (Cu(II)) via a Cu(I)-S-...

1a [K(P3C2Mes2)] 1b [K(P3C2Bu2)] 2 [(μ,η:η:η-P3C2Mes2)2{Cu(CH3CN)}2{Cu(CH3CN)2}]x[Cl]x 3 [(μ,η:η:η-P3C2Mes2){Cu(CH3CN)(μ2-Cl)}4{K(μ2-dme)}{Cu(CH3CN)0.5(μ2-Cl)}]x 4 [(μ,η:η:η-P3C2Mes2){Cu(CH3CN)(μ2-Br)}4{K(μ2-thf)}{Cu(μ2-Br)}]x 5 [(μ,η:η:η-P3C2Mes2){Cu(CH3CN)(μ2-I)}2{Cu(CH3CN)(μ3-I)}2Cu]x 6 [(μ,η:η:η-P3C2Mes2){Cu(CH3CN)(μ3-I)}2{Cu(CH3CN)(μ4-I)}2Cu2{Cu(CH3CN)}(μ3-I)(μ2-I)]x 7 [(μ,η:η:η-P3C2tBu2)(...

Two 28-d experiments were conducted to evaluate the efficacy of low dietary concentrations of Cu as Cu-proteinate compared with 250 ppm Cu as CuSO4 with growth performance, plasma Cu concentrations, and Cu balance of weanling swine as the criteria. In the production study (Exp. 1), 240 crossbred pigs that averaged 19.8 d of age and 6.31 kg BW initially were group-fed (two or three pigs per pen)...

O sx O sx O sx O sx O sx O sx O sx O sx O sx +++++ p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce ll p er iv as cu la r ce...

The attractive interactions that exist between d “closedshell” elements of Group 11 have received extensive attention. 2] The term “aurophilicity” has been coined to describe the Au Au bonding interactions that are evident in many molecular and solid-state structures and have been attributed to correlation and relativistic effects. However, relativistic effects cannot be invoked for Cu···Cu int...

The present work highlights recent advances in elucidating the methane oxidation mechanism of inorganic Cu-ZSM-5 biomimic and in identifying the reactive intermediates that are involved. Such molecular understanding is important in view of upgrading abundantly available methane, but also to comprehend the working mechanism of genuine Cu-containing oxidation enzymes.