Gold nanorods stabilized by binary ligand mixtures of cetyltrimethylammonium bromide (CTAB, primary ligand) and ascorbic acid or hydroquinone were investigated complementary synchrotron radiation-induced spectroscopies microscopies, with the aim...

The phenomenon of molecular binding, where two molecules, referred to as a receptor and ligand, bind together form ligand-receptor complex, is ubiquitous in biology essential for the accurate functioning all life-sustaining processes. probability single forming complex with any one L surrounding ligand molecules at thermal equilibrium can be derived from partition function obtained Gibbs-Boltzm...

Cell adhesion on a supported lipid bilayer (SLB) functionalized with ligand proteins is widely-used cell-mimetic model for the study of trans receptor-ligand interaction that mediates adhesion, and has been shown to play an important role in unravelling molecular players cell adhesion. Experimental studies such cell-SLB systems often assume there no cis interactions between ligands. An question...

A new theory of ligand-receptor bonds in biological cells that accounts for membrane fluctuations reveals an orders-of-magnitude increase binding rates and the range over which a receptor can recognize its ligand.

N-nitroso compounds, such as N-nitrosodiethylamine (NDEA), can be formed by the reaction of secondary amines with nitrosating agents, and are suspected to be involved in tumors in humans. NDEA has been considered a weak carcinogen in genotoxic assays probably due to the inefficient nitrosamine activation system that is used and/or to the efficient repair system. In this work, we evaluated the s...

Recent years have witnessed substantial research activities in the field of chemistry and biochemistry of nitric oxide (NO) because of the remarkable discoveries of its key roles in a wide range of human physiological processes.1 As a unique class of such NO-carrying vehicles, S-nitrosothiols (RSNOs) are generally believed to take a most active part in many biological functions of nitric oxide ...

Several possible risk factors for brain tumors have been suggested in the past, including N-nitroso compounds, but with the exception of ionizing radiation, none has been consistently confirmed. The present study was aimed at assessing the influence of nutritional factors, including N-nitroso compounds, in the etiology of brain tumors, specifically gliomas and meningiomas. One hundred and thirt...

BACKGROUND Animal studies have demonstrated that iron may be related to carcinogenesis, and human studies found that heme iron can increase the formation of N-nitroso compounds, which are known carcinogens. OBJECTIVES One of the postulated mechanisms linking red meat intake to cancer risk involves iron. Epidemiologic studies attempt to investigate the association between heme iron intake and ...

a pvc membrane ni(ii) ion selective electrode has been constructed using (1e,2e)-bis(2-aminophenyl)n'1,n'2-dihydroxyethanebis as membrane carrier. the electrode exhibited a goodpotentiometric response for ni(ii) over a wide concentration range 1.0×10-4 to 1.0×10-1m with aslope of 29.4±0.5 mv/decade a and a working ph range of 6.5-9.0. it had a fast response time of≤20s. the best performance was...