Dermal sinuses are well-characterized lesions (1-3). A patient with a dermal sinus frequently has a hairy nevus or dimple overlying the tract. Yet, despite having this cutaneous marker, these patients often seek medical attention only after they suffer an infectious complication of the tract. Although infection most commonly will occur in the form of a cutaneous abscess, another more serious an...

Mucormycosis is a life-threatening fungal infection caused by group of moulds known as mucormycetes. It viral disease, increasingly progressive, rapidly triggers in diabetic, immunocompromised and trauma patients. Diabetic patients seem to have the classic rhinocerebral variant. Rhinocerebral mucormycosis begins nasal cavity, paranasal sinus, orbital soft tissue infection. In immunocompetent pa...

septic arthritis with polyarticular presentation is an uncommon clinical entity. a case of complicated staphylococcal infection with purulent and reactive polyarthritis, osteomyelitis, cutaneous and pleuropericardial involvement as well as transient blindness is presented here.

Integrins have been shown to play important roles in embryonic development, wound healing, metastasis, and other biological processes. alphavbeta5 is a receptor for RGD-containing extracellular matrix proteins that has been suggested to be important in cutaneous wound healing and adenovirus infection. To examine the in vivo function of this receptor, we have generated mice lacking beta5 express...

BACKGROUND Extrahepatic manifestations are seen in association with chronic infection by hepatitis B or C virus including cutaneous disorders. The frequency of these findings seems to vary among different places and reports. There is a lack of information about this issue in Brazil. OBJECTIVES To estimate the prevalence of cutaneous findings affecting HBV or HCV carriers from a reference outp...

Cutaneous complications of Bacillus Calmette-Guerin (BCG) vaccine, especially in the form of generalised disease, are uncommon and mostly occur in immunocompromised individuals. There is a paucity of data on the cutaneous adverse reactions secondary to BCG immunotherapy in leprosy. We report two unique cases of disseminated cutaneous BCG infection following immunotherapy in patients with leprom...

Skin diseases ranging from infective dermatitis to cutaneous lymphoma have been associated with human T cell leukemia virus (HTLV) type I. A generalized exfoliative papillated dermatopathy occurred in a rabbit 20 months into a course of chronic HTLV-I infection. Biopsies revealed epidermotropic T cell infiltrates, including Sezary-like cells, that resulted in a pattern mimicking cutaneous T cel...

Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms. These cases require immediate diagnosis a...

Patients with systemic lupus erythematosus (SLE) who present with skin disease pose the clinician with diagnostic challenges. The skin disease can reflect an increase in systemic disease activity suggested by other features of active lupus and, as such, usually responds well to more aggressive immunosuppressive therapy. Other possibilities of skin disease include drug eruptions, skin disease un...

Following an epidemiological survey of zoonotic cutaneous leishmaniosis (ZCL) in some villages of Badrood, a rural district north of the city of Natanz, central Iran, Phlebotomus (Phlebotomus ) papatasi Scopoli were found to be naturally infected with Leishmania (Leishmania) major zymodeme MON-26. Sandflies were collected and dissected biweekly from rodent burrows during sandfly season, Ap...