Cutaneous epithelioid angiomatous nodule (CEAN) is a rare benign vascular proliferation recently described by Brenn and Fletcher.1 It typically develops in adults as a solitary, small, reddish, fast-growing nodular lesion most frequently located on the trunk or limbs.2 Histologically it consists of an infiltration of epithelioid cells, with abundant eosinophilic cytoplasm and vesicular nuclei w...

Rheumatoid Arthritis (RA) is a chronic systemic inflammatory disease which can involve tissues and organs other than the synovial joints. RA patients with skin manifestations usually have severe disease. Rheumatoid nodule is the most common skin manifestation seen in RA. Other skin conditions commonly described in RA are rheumatoid vasculitis, raynaud’s phenomenon and neutrophilic dermatoses. D...

Cutaneous adenoid cystic carcinoma (CACC) is an extremely rare neoplasm of head and neck region, and is characterized by propensity for local recurrence and perineural invasion. Late distant metastases occur usually to lungs. Although patients with lung metastases from CACC cannot be cured, long-term survival may be possible due to its slow-growing malignancy. We report a case of a 69-year-old ...

Granular cell tumor (GCT) is a rare benign neoplasm of the skin that accounts for 0.5% of all soft-tissue tumors. The tumor mostly presents with a symptomatic slowly growing solitary nodule and overlying normal skin; therefore, it is not always considered in the differential diagnosis. Here, we report a 58-year-old female patient who presented with a 4-year history of a slowly growing mass, wit...

This case report states a 25-year-old woman, residing in the city of Dezfool, Khuzestan Province, south of Iran with the diagnosis of cutaneous leishmaniasis in June 2008. Her skin lesion had developed from 8 months earlier as a nodule on her left arm, 1×3 cm in diameter. Because of severity of the lesion, we prescribed meglumine antimoniate intralesionally with giving up her breast feeding. Af...

Leprosy is a chronic granulomatous infection, caused by mycobacterium leprae, primarily affecting the peripheral nerve trunks and cutaneous nerves. It classically presents with neural or dermal signs and symptoms. The indolent course of leprosy may manifest as erythema nodosum (appearance of tender inflamed subcutaneous nodule) and reversal reaction (inflammation in the previous skin lesion, ap...

Piloleimyoma is a type of cutaneous leiomyoma arising from arrectores pilorum. It can present as either a solitary nodule or multiple lesions. Usually it is localized on the extremities, but can also occur on trunk, neck area and face. Lesions are usually cold, ulcerated and spontaneously painful. Herein we report a case of piloleiomyoma with cytological atypia that was painless despite the pre...

Cutaneous metastases of rectal adenocarcinoma is a rare phenomenon. We present a 65 year-old man with a painless nodule on the scrotal skin. Excisional biopsy of the nodules revealed a metastasis from rectum adenocarcinoma. Afterwards, the left scrotum was treated with a radiation therapy and the patient also received a salvage chemotherapy. The patient is still alive without any distant metast...

KOH: potassium hydroxide INTRODUCTION Aspergillus sp, Candida sp, and zygomycoses can disseminate rapidly in an immunocompromised host, causing significant morbidity and mortality. Serum testing, tissue biopsy, and culture are used to confirm a suspected diagnosis, but waiting for results may delay initiation of life-saving treatment. We report a case of disseminated aspergillosis presenting wi...

Eccrine angiomatous hamartoma (EAH) is a rare, benign cutaneous tumor. It is characterized by the proliferation of the eccrine gland elements that are closely associated with capillary proliferation. Patients usually present with a solitary nodule on the extremities that appeared at birth or during the prepubertal years. We report a rare case of EAH in a 13-year-old boy, with clinical features ...