This paper reviews current and future applications of Artificial Intelligence (AI) and Knowledge-Based systems to manufacturing. This is not a review of robotics technology, but focuses, instead, on manufacturing decision problems. Manufacturing, in this case, refers to the entire product life cycle: product design, production planning, production, distribution, and field service and reclamatio...

Several microRNAs have been implicated in human breast cancer but none to date have been validated or utilized consistently in clinical management. MicroRNA-301 (miR-301) overexpression has been implicated as a negative prognostic indicator in lymph node negative (LNN) invasive ductal breast cancer, but its potential functional impact has not been determined. Here we report that in breast cance...

Several microRNAs have been implicated in human breast cancer but none to date have been validated or utilized consistently in clinical management. MicroRNA-301 (miR-301) overexpression has been implicated as a negative prognostic indicator in lymph node negative (LNN) invasive ductal breast cancer, but its potential functional impact has not been determined. Here we report that in breast cance...

We previously reported that telomerase-specific replication-component adenovirous, Telomelysin (OBP-301) has cytotoxic activity to the YCUT892, KCCT873, KCCT891, KCCL871, YCUM862, HN12, and KCCOR891 cell lines in vitro, and investigated the association between cytotoxic activity and adenoviral receptor expression. In this study, we evaluated the most appropriate way to administer telomelysin (O...

in this work, effects of homogenization time of 3 to 13 h at 1200 °c on the grain refinement of as-cast aisi 301 stainless steel after different hot rolling conditions were investigated. the results showed that the minimum grain size of 16±7 mm was achieved when homogenization took place at 1200 °c for 9 h followed by hot rolling at temperature range of 1000–1200 °c with strain of 0.8 and strai...

Monoclonal antibody Cat-301 recognizes a cell-surface proteoglycan on subsets of neurons in several areas of the cat and macaque monkey central nervous system. In striate and extrastriate visual cortex of the macaque, the distribution of Cat-301-positive neurons demonstrates features of cellular organization that correlate with previously described functional subdivisions. Here we show that Cat...

The purpose of this study was to determine the efficacy and the possible mechanism of action of a recently synthesized drug, TAS-301 [3-bis(4-methoxyphenyl)methylene-2-indolinone], on stenosis after balloon overstretch injury of porcine arteries. We measured the diameter of vessels by angiography and conducted histological analysis. The oral administration of TAS-301 kept dilated the angiograph...