The volatile compounds from various parts of Echinops ilicifolius (Compositae) such as flowers, leaves and roots obtained by hydrodistillation (HD) and headspace solid-phase microextraction (HS-SPME) methods were subsequently analysed by GC and GC/MS and compared. Thirty-seven and 20 components of the flower of E. ilicifolius were characterized, representing 99.7% and 100.0% of the total compos...

the composition of the essential oils of two african (“white” and “yellow”) olibanums available in the commercial market of isfahan (iran) was analyzed by gas chromatography (gc) and gc-mass spectroscopy methods. the main constituents of the “white” olibanum oil were alpha-pinene (34.8%), limonene (15.9%), alphathujene (9.0%), para-cymene (7.0%), myrcene (6.2%) and sabinene (6.0%). major compon...

The highly porous and robust [Ni(8)(OH)(4)(OH(2))(2)(4,4'-(buta-1,3-diyne-1,4-diyl)bispyrazolato)(6)](n) MOF can be used as a proof of concept for the incorporation and release of the non-conventional [Ru(p-cymene)Cl(2)(pta)] RAPTA-C metallodrug.

Esterification of (4-hydroxyphenyl)diphenylphosphine, coordinated to the [Ru(η6-p-cymene)Cl2] fragment, allows a series of bioactive carboxylic acids to be introduced directly into the organometallic molecule. Evaluation of the compounds on human ovarian cancer cells reveals synergistic enhancements in their antiproliferative activity relative to their bioactive organic and organometallic precu...

The complex [(p-cym)Ru(bpm)(py)][PF(6)](2) (where p-cym = para-cymene, bpm = 2,2'-bipyrimidine and py = pyridine) is the first ruthenium(ii) arene complex that can selectively photodissociate a monodentate ligand (py) when excited with visible light and form a reactive aqua derivative able to bind to a DNA base.

We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η(6)-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.

Satureja wiedemanniana (Lallem.) Velen (Lamiaceae) is an endemic species of Turkey. Aerial parts of the plant collected from eleven different localities in Turkey were subjected to hydrodistillation to yield essential oils which were analysed by a GC/MS system. Carvacrol, thymol, p-cymene and gamma-terpinene were found as the main constituents. Antibacterial evaluation of the oils was also carr...

Ruthenium/Me-BIPAM-catalyzed asymmetric addition of arylboronic acids to methyl 2-formylbenzoates afforded chiral 3-aryl-isobenzofuranones. [RuCl2(p-cymene)]2/Me-BIPAM and RuCl2(PPh3)3/Me-BIPAM catalyst systems tolerate a variety of functional groups and give high yields with high enantioselectivities.

The activation of the C-H bond of 1-phenylpyrazole (2) and 2-phenyl-2-oxazoline (3) by [Ru(OAc)2(p-cymene)] is an autocatalytic process catalyzed by the co-product HOAc. The reactions are indeed faster in the presence of acetic acid and water but slower in the presence of a base K2CO3. A reactivity order is established in the absence of additives: 2-phenylpyridine>2-phenyl-2-oxazoline>1-phenylp...

To determine the period of harvest that optimizes the antimicrobial activities of the essential oil of Ocimum gratissimum L. from Benin, aerial plant parts were collected at two vegetative stages (pre- and full-flowering) and three sampling times (7 am, 1 pm, and 7 pm). Extraction by hydrodistillation yielded between 0.65 and 0.78% of essential oils. Characterization of the oils by GC-FID and G...