PURPOSE Radical cystectomy (RCx) is perhaps the most effective therapeutic approach for patients with muscle-invasive bladder cancer. Unfortunately, clinical staging is imprecise and the degree of understaging remains high. This study retrospectively evaluated patients undergoing RCx with regard to pathologic outcomes and degree of upstaging to better identify features that may lessen clinical ...

Background: Platinum-based pre-operative chemotherapy (POC) for muscle-invasive bladder cancer (MIBC) increases the complete pathological response rate at cystectomy and improves overall survival. However, 60% of MIBC patients still has muscle-invasive disease at cystectomy despite POC. Therefore, accurate prediction of response to POC is an important clinical need. We hypothesized that an elev...

OBJECTIVES To evaluate the outcomes of patients with muscle-invasive Stage T2-4a bladder carcinoma managed by transurethral surgery and concurrent chemoradiation. METHODS A total of 190 patients were treated on institutional prospective protocols using concurrent cisplatin-containing chemotherapy and radiotherapy after rigorous transurethral resection of the bladder tumor. Patients were re-ev...

A large maxillary cyst was treated for 3 months with marsupialization and decompression, followed by surgical endodontic therapy of the affected teeth and cystectomy. Although small cystic lesions will typically heal with nonsurgical endodontic therapy, larger lesions may need additional treatment. Surgical enucleation of a large cystic lesion may lead to damage of other teeth or anatomic struc...

Purpose: The development of ureteral strictures is a complicated problem for patients who have had urinary reconstruction at the time of radical cystectomy. Management options range from conservative approaches with minimally invasive options such as balloon dilation and stent placement to the more invasive options with open or laparoscopic surgical repair. The purpose of this study was to revi...

PURPOSE Should the surgeon proceed with surgery when grossly positive nodes are found at cystectomy? To answer this question, we determine the outcome of patients after radical surgery alone for grossly node positive bladder cancer. MATERIALS AND METHODS A total of 84 patients with grossly node positive (N2-3) bladder cancer found at cystectomy underwent extended pelvic lymph node dissection ...

CONTEXT Although open radical cystectomy (ORC) is still the standard approach, laparoscopic radical cystectomy (LRC) and robot-assisted radical cystectomy (RARC) have gained popularity. OBJECTIVE To report a systematic literature review and cumulative analysis of perioperative outcomes and complications of RARC in comparison with ORC and LRC. EVIDENCE ACQUISITION Medline, Scopus, and Web of...

SIMPLE cystectomy has proved to be a satisfactory method of treatment for carcinoma of the urinary bladder. We became interested in this method of treatment in 1948 and have performed 265 cystectomies since then. During the period between 1948 and 1953, ureterosigmoidostomy was utilized as a means of urinary diversion. Since then, we have been using the ileal loop as a method of urinary diversi...

Introduction. Bladder cancer is the 10th most common worldwide. Radical cystectomy remains gold standard for muscle invasive bladder cancer. The active use of robot-assisted treating patients with allows considering it as an alternative surgical option. review aimed at collecting and systematizing evidence base intracorporeal cystectomy. Materials methods. MEDLINE, Scopus, Clinicaltrials.gov, G...

PURPOSE We defined an optimal curative strategy for muscle invasive bladder cancer and to determine how best to deliver curative therapy. MATERIALS AND METHODS We reviewed published reports from 1985 to 2006 dealing with the treatment of muscle invasive (stage T2-T4a) bladder cancer. We analyzed all cohort, phase II and randomized phase III studies providing level 1 to 3 evidence impacting su...