aim : the purpose of this study was to assess the incidence of 16bp insertion of intron 3 p53 in gastritis lesion and its correlation with clinicopathological aspects. background : p53 alterations have been implicated in the development of gastric malignancies. patients and methods : 97 gastritis and normal adjacent tissues were investigated for p53 gene analysis using pcr-sequencing of intron3...

in this study we estimated the allele and genotype frequencies of scd1 and dgat1 gene polymorphism. the analysis was conducted on 408 holstein cows from five dairy herds in isfahan province. genotypes were identified using pcr-rflp technique. two genetic variants (a and v) of the scd1 gene were observed in this experiment. the frequency of a-allele ranged from 0.49 to 0.66, while frequency of v...

tuberculosis is one of the most common infectious diseases in the world. in recent years, genetically approach has been developed. one of the interesting gene for investigator is ifn-γr1. in this study we determind susceptibility to tuberculosis with polymorphism of ifn-γr1 gene. fifthly patients with smear positive tuberculosis have been chosen randomly. they were matched with 54 healthy contr...

in this study the genetic polymorphism of growth hormone (gh) gene as a candidate gene in livestock was investigated. blood samples were randomly collected from 34 alpine and 42 saanen goats. dna was extracted from blood samples and a 365 bp region of exon 5 of the gh genewas amplified by polymerase chain reaction (pcr). pcr products were analyzed using single strand conformation polymorphism (...

fibroblast growth factor 2 (fgf2) serves in the uterine endometrium during estrous presenting in the bovine mammary gland which is responsible to express interferon-t (ifnt), and is an important agent to encourage the continuation of pregnancy in the ruminants. significant associations have been found between genes affected by ifnt and genes that are responsible for milk production traits. seme...

in view of the fundamental role of genetics in development of obesity, the present study aimed to investigate the single nucleotide polymorphism of some obesity-related genes among a subset of obese women living in tabriz, iran. for this purpose, 70 eligible obese women (aged 18-45 years) were genotyped for the uncoupling protein-1 (ucp-1) -3826a>g, ß3-adrenergic receptor (ß3adr) trp64arg, lept...